Results 151 to 160 of about 4,828,539 (266)

How a Mandatory Activation Program Reduces Unemployment Durations: The Effects of Distance [PDF]

In an experimental setting some Danish unemployed workers were assigned to an activation program while others were not. Unemployed who were assigned to the activation program found a job more quickly. We show that the activation effect increases with the
Ours, J.C. van, Graversen, B.K.
core  

Complement activation in immune thrombotic thrombocytopenic purpura: Possible amplifier and potential therapeutic opportunity. [PDF]

Hemasphere
Cugno M, Cataland SR, Lämmle B.
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Comparative efficacy of ultrasonic, diode laser, and manual irrigant activation around an apically separated instrument: an in vitro study. [PDF]

BMC Oral Health
Asfor KA, Leheta NA, Moussa SM.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Is there an alternative to grant-funding for sexual and reproductive health advocacy? A survey of the income base of AmplifyChange grantees

Sexual and Reproductive Health Matters, 2023
Alex le May, Lucie Hazelgrove-Planel
doaj   +1 more source

Psychosocial Factors and Patient Activation in Ocular Trauma: An Exploratory Cross-Sectional Path Analysis. [PDF]

J Multidiscip Healthc
Jiang H, Shi L, Mao F, Bai J.
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Renin-Angiotensin Signaling and Vascular Function: Insights into Health and Disease. [PDF]

Acta Physiol (Oxf)
Bertoldi G, Sonkusare SK.
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source