Results 81 to 90 of about 2,095,505 (265)
Actively Seeking Activating Sequences [PDF]
I thank R. Brent, I. Cartwright, L. Keegan, Z. Liu, M. Ptashne, and M. Xu for comments. I apologize that the page limit did not permit citation of all relevant work. This work was supported in part by the AHA and the NSF.
openaire +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The PM10 concentrations in the studied region (Ostravsko-karvinská agglomeration, Czech Republic) exceed air pollution limit values in the long-term and pose a significant problem for human health, quality of life and the environment.
Irena Pavlíková +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M +14 more
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Biological control of Colletotrichum panacicola on Panax ginseng by Bacillus subtilis HK-CSM-1
Background: Biological control of plant pathogens using benign or beneficial microorganisms as antagonistic agents is currently considered to be an important component of integrated pest management in agricultural crops.
Hojin Ryu +5 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Role of phosphoinositide 3-kinases in mast cell activation [PDF]
Mast cells are primary effector cells in allergy and chronic inflammation. Class IB (PI3Kγ) and class IA (PI3Kδ) PI3K have been shown to play major roles in mast cell activation: antigen/IgE stimulation triggers autocrine/paracrine activation of mast ...
Collmann, Emilie
core +1 more source

