Results 21 to 30 of about 2,095,505 (265)
Cooperative redox activation for carbon dioxide conversion
Nature Communications, 2016 While CO2 can be converted to CO for further reactivity, typically this involves the generation of large amounts of waste. Here the authors report the conversion of CO2to CO, with the siloxane by-product being further used in a carbonylative Hiyama ...
Zhong Lian +4 more
doaj +1 more source
, 2022 Hydrogen is a widely used reductive reagent in organic synthesis. The direct reactions between dihydrogen and other organic compounds are very difficult, due to the high stability of hydrogen molecules.
Xinchen, HE +7 more
core +1 more source
Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]
, 2009 The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Ross, Emma +10 more
core +1 more source
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse
Nature Communications, 2019 The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear.
Andres Ernesto Zucchetti +10 more
doaj +1 more source
Not All Immune Checkpoints Are Created Equal
Frontiers in Immunology, 2018 Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in ...
Annika De Sousa Linhares +3 more
doaj +1 more source
Nature Communications, 2022 Immunoglobulin M (IgM) is the Ig isotype that serves as the first line of host defence during infection. Here, the authors image the full-length IgM pentamer by cryo-EM, revealing the structure and hinge motion of the antigen binding domains.
Qu Chen +4 more
doaj +1 more source
FcγR requirements and costimulatory capacity of Urelumab, Utomilumab, and Varlilumab
Frontiers in Immunology, 2023 IntroductionTargeting costimulatory receptors of the tumor necrosis factor receptor (TNFR) superfamily with agonistic antibodies is a promising approach in cancer immuno therapy.
Judith Leitner +4 more
doaj +1 more source
Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility
EMBO Molecular Medicine, 2018 Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter +9 more
doaj +1 more source
Scientific Reports, 2018 A phosphoiminoBINOL ligand was designed to form a dinuclear metal complex that could hold a malononitrile molecule. The dinuclear bis(phosphoimino)binaphthoxy-Pd2(OAc)2 complex catalyzed a double Mannich reaction of N-Boc-imines with malononitrile to ...
Takayoshi Arai +4 more
doaj +1 more source
Cells, 2021 LAT is an important player of the signaling cascade induced by TCR activation. This adapter molecule is present at the plasma membrane of T lymphocytes and more abundantly in intracellular compartments.
Juan José Saez +5 more
doaj +1 more source