Results 191 to 200 of about 7,192,603 (344)

CLAMP and Zelda function together to promote Drosophila zygotic genome activation

, 2021
Jingyue Duan, Leila E. Rieder, Megan M Colonnetta, Annie Huang, Mary Mckenney, Scott Watters, Girish Deshpande, William T. Jordan, Nicolas L. Fawzi, Erica Larschan   +9 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Tuning metal–metal interactions for cooperative small molecule activation

, 2021
Qiuran Wang, Sam H. Brooks, Tianchang Liu, Neil C. Tomson   +3 more
openalex   +2 more sources

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

Cell, 2018
Ann Boija, Isaac A. Klein, Benjamin R. Sabari, Alessandra Dall’Agnese, Eliot L. Coffey, A. V. Zamudio, Charles H. Li, Krishna Shrinivas, John C. Manteiga, N. Hannett, B. Abraham, Lena K. Afeyan, Y. Guo, Jenna K. Rimel, Charli B. Fant, Jurian Schuijers, Tong Ihn Lee, D. Taatjes, R. Young   +18 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cell-specific roles of autophagy in liver fibrosis: implications for targeted pharmacotherapy. [PDF]

Ann Med
Liu C, Yang H, Liu Y, An M, Weng Z, Li L.   +5 more
europepmc   +1 more source

D‐series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury

, 2013
Takuya Miyahara, Sara J. Runge, Anuran Chatterjee, Mian Chen, Giorgio Mottola, Jonathan M. Fitzgerald, Charles N. Serhan, Michael S. Conte   +7 more
openalex   +1 more source

Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference [PDF]

, 2019
Min‐Ho Nam, Kyung‐Seok Han, Jaekwang Lee, Woojin Won, Wuhyun Koh, Jin Young Bae, Junsung Woo, Jayoung Kim, Elliot Kwong, Tae-Yong Choi, Heejung Chun, Seung Eun Lee, Gi-Chang Kim, Ki Duk Park, Se‐Young Choi, Yong Chul Bae, C. Justin Lee   +16 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Thyroarytenoid muscle fiber orientation regulates the ability to modulate vocal fold vertical thickness. [PDF]

PLoS One
Yoshinaga T, Zhang Z.
europepmc   +1 more source