Results 211 to 220 of about 7,192,603 (344)

ApoE4 Homozygosity Is Associated With Increased Microglia Activation in Fatal COVID-19. [PDF]

Neuropathology
Hamdan A, El-Amri Y, Heinrich F, Mohamed OAA, Sepulveda-Falla D, Glatzel M, Matschke J, Krasemann S.   +7 more
europepmc   +1 more source

Sulfate Resistance of Alkali Activated Pozzolans [PDF]

, 2014
Dali Bondar, C.J. Lynsdale, N.B. Milestone, N. Hassani   +3 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Lack of Negative Feedback Loops of CTLA-4 and PD-L1 as Key Mechanisms for Post-Acute T Cell Activation Until 3 Months After Ischemic Stroke. [PDF]

Int J Mol Sci
Peglau L, Ruhnau J, Winkelmann M, Krüger T, Dressel A, Schulze J, Vogelgesang A.   +6 more
europepmc   +1 more source

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

EMBO Journal, 1991
R. Schreck, Peter Rieberl, P. Baeuerle
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Effect of gutta-percha cone-mediated ultrasonic activation on the push-out bond strength and dentinal tubule penetration of epoxy resin- and silicate-based root canal sealers: an in vitro study. [PDF]

BMC Oral Health
Kandemir B, Ozasir T, Ozasir B, Gulsahi K.   +3 more
europepmc   +1 more source

TGF‐β1 activates RSC96 Schwann cells migration and invasion through MMP‐2 and MMP‐9 activities [PDF]

, 2019
Antonella Muscella, Carla Vetrugno, Luca Giulio Cossa, Santo Marsigliante   +3 more
openalex   +1 more source

STUDIES ON THE ACTIVATION OF CATALASE ACTIVITY

The Japanese Medical Journal, 1948
openaire   +3 more sources

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma

Science, 1997
V. Kořínek, Nick Barker, P. Morin, D. V. van Wichen, R. D. de Weger, K. Kinzler, B. Vogelstein, H. Clevers   +7 more
semanticscholar   +1 more source