Results 251 to 260 of about 7,259,671 (332)

Neural basis of intensity-dependent brain activity in response to mechanical stimulation and the level of pain sensitivity. [PDF]

Front Hum Neurosci
Kawamura R, Sasaki K, Shimizu S, Kodama N.   +3 more
europepmc   +1 more source

To ancillary and beyond: CO2 activation and redox activity of NN chelate actor ligands

, 2017
Trevor Janes
openalex   +1 more source

Novel Extracted Piperine as an Activatable Molecular Sensor Toward Viscosity Detection in Liquid System

Lingfeng Xu, Yanrong Huang, Xuefei Zhong, Lili Zeng, Xinmin Deng, Yu Xie, Haibin Li   +6 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A pair of interneurons that confer positive real-time valence to sweet sensation in Drosophila. [PDF]

Curr Biol
Christie KW, Dadyala TS, Sinakevitch IT, Chung P, Ito M, Shao L.   +5 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Learning cardiac activation and repolarization times with operator learning. [PDF]

PLoS Comput Biol
Ziarelli G, Centofanti E, Parolini N, Scacchi S, Verani M, Pavarino LF.   +5 more
europepmc   +1 more source

Salt-Induced Cell Division and Transcriptional Activation in Synchronized Suspension Cells of the Common Ice Plant (Mesembryanthemum crystallinum L.)

Phu Thuong Nhan Nguyen, Sakae Agarie, Yuri Kondo   +2 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Neural Correlates of Cognitive Gains Induced by Commercially Available Cognitive Training Programs: A Meta-Analysis of Neuroimaging Studies. [PDF]

Brain Sci
Wang Z, Liu Y, Liu C, Li G.
europepmc   +1 more source