Results 251 to 260 of about 7,192,603 (344)

HIV-1 and Its Strategy for Hiding Viral cDNA from STING-Mediated Innate Immunity. [PDF]

Int J Mol Sci
Mashkovskaia A, Agapkina Y, Oretskaya T, Gottikh M, Anisenko A.   +4 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE-Mediated Anaphylaxis. [PDF]

Immunol Rev
Biswas R, Fried JM, Curotto de Lafaille MA.   +2 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

HDAC1 dysregulation promotes pro-inflammatory microglial activation and aggravates post-stroke neuroinflammation. [PDF]

Ann Med
Chen JS, Wang HK, Su YT, Ho YC, Liang CL, Lee YK, Chu TH, Lin YS, Wu CC.   +8 more
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Perspective on the Development of Monomer Recovery Technologies from Plastics Designed to Last

ACS Organic & Inorganic Au
Steffan K. Kristensen, Alexander Ahrens, Bjarke S. Donslund, Troels Skrydstrup   +3 more
doaj   +1 more source

Butyrophilin 3A/2A1-independent activation of human Vγ9Vδ2 γδ T cells by bacteria. [PDF]

PNAS Nexus
Gombert D, Simeonov J, Klein K, Agaugué S, Scheffold A, Kabelitz D, Peters C.   +6 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source