Results 101 to 110 of about 60,175,050 (353)

Classificação de cerâmicas arqueológicas da Bacia Amazônica Classification of archaeological ceramics from the Brazilian Amazon Basin

open access: yesQuímica Nova, 2001
In order to elucidate the traditional classification of archaeological artefacts, a multielemental analytical method for characterisation of its micro and macro chemical constituents.
Rose Mary Latini   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Modelling the activation of words in human memory : the spreading activation, spooky-activation-at-a-distance and the entanglement models compared [PDF]

open access: yes, 2011
Modelling how a word is activated in human memory is an important requirement for determining the probability of recall of a word in an extra-list cueing experiment.
Bruza, Peter D.   +14 more
core   +1 more source

Uranium foil neutron activation analysis

open access: yesActa Polytechnica
At the Department of Nuclear Reactors of the Faculty of Nuclear Sciences and Physical Engineering of the Czech Technical University (FNSPE CTU) in Prague, there is a need to implement a neutron activation analysis as a tool for the separation of uranium
Ján Kozic, Milan Štefánik
doaj   +1 more source

Prompt Gamma Activation Analysis at the Budapest Research Reactor

open access: yes, 2012
Prompt gamma activation analysis is a powerful method, but it is not yet well enough known in the nuclear data community. For this reason, we describe the PGAA measurement and data evaluation processes, as well as the energy and spatial distribution ...
T. Belgya
semanticscholar   +1 more source

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

open access: yesScience, 2018
Lysosomes keep neuronal stem cells young An important consequence of aging is loss of regenerative capacity in stem cells, particularly those of the nervous system. Leeman et al.
D. Leeman   +15 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Assessment of Heavy Metal Contamination of Coal Deposits in Kogi State, Nigeria using Instrumental Neutron Activation Analysis [PDF]

open access: yesPhysics Access
In this study, the concentration of heavy metal contaminants in the coal samples from selected coal mining sites in Okobo, Odagbo, Ofugo and Opoko-Obido, within Kogi State, Nigeria were identified and determined using the Instrumental Neutron Activation ...
Felix O Uloko   +2 more
doaj   +1 more source

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