Results 121 to 130 of about 2,855,411 (314)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Neutron activation analysis in Mediterranean Archaeology: current applications and future perspectives. [PDF]

Archaeol Anthropol Sci, 2023
Riehle K, Kistler E, Öhlinger B, Heitz C, Ben-Shlomo D, Jung R, Mommsen H, Sterba JH, Gimatzidis S, Fantalkin A, Prillwitz S, Hein A, Geissler L, Lehmann G, Kindberg Jacobsen J, Posamentir R, Schlotzhauer U.   +16 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

On Mandatory Activation of Welfare Recipients [PDF]

This paper investigates whether mandatory activation programs for welfare recipients have effects on welfare participation, employment and disposable income. In contrast to earlier studies, we are able to capture both entry and exit effects.
Dahlberg, Matz, Mörk, Eva, Johansson, Kajsa   +2 more
core  

ESKAPE Act Plus: Pathway Activation Analysis for Bacterial Pathogens. [PDF]

mSystems, 2022
Koeppen K, Hampton TH, Neff SL, Stanton BA.   +3 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Covalently bound substrate at the regulatory site triggers allosteric enzyme activation [PDF]

, 2008
The mechanism by which the enzyme pyruvate decarboxylase from yeast is activated allosterically has been elucidated. A total of seven three-dimensional structures of the enzyme, of enzyme variants or of enzyme complexes form two yeast species (three of ...
Steffen Kutter, König, Stephan, Kutter, Steffen, Manfred Weiss, Golbik, Ralph, Michael Spinka, Stephan König, Georg Wille, Ralph Golbik, Spinka, Michael, Weiss, Manfred S., Wille, Georg   +11 more
core   +1 more source

Elemental profile of dietary supplements and agricultural byproducts evaluated by neutron activation analysis. [PDF]

J Radioanal Nucl Chem, 2022
De Nadai Fernandes EA, Furlan GN, Lima RC, Bacchi MA, Sarriés SRV, Sarriés GA.   +5 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection. [PDF]

STAR Protoc, 2022
Tsutsuki H, Zhang T, Yahiro K, Toyomoto T, Sawa T.   +4 more
europepmc   +1 more source