Results 231 to 240 of about 17,207,076 (361)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Efficient Neural Networks on the Edge with FPGAs by Optimizing an Adaptive Activation Function. [PDF]

Sensors (Basel)
Jiang Y, Vaicaitis A, Dooley J, Leeser M.   +3 more
europepmc   +1 more source

A ‘sweet spot’ for complement receptor CD46 activity: CYT-1 regulates glycolytic and moonlighting functions of glycolytic enzymes during human CD4+ T cell activation

Natalia Kunz, Gaëlle Le Friec, Jack Bibby, Erin E. West, Ayden Case, Parul Singh, Nicolas S. Merle, Paul Lavender, Majid Kazemian, Christoph Hess, Claudia Kemper   +10 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Sub-milliwatt threshold power and tunable-bias all-optical nonlinear activation function using vanadium dioxide for wavelength-division multiplexing photonic neural networks. [PDF]

Sci Rep
Parra J, Navarro-Arenas J, Sanchis P.
europepmc   +1 more source

Functional imaging of astrocyte activity

Neural Regeneration Research, 2021
Hiroki Kato, Tatsusada Okuno
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins. [PDF]

PLoS One
Liu X, Matsuyama Y, Sugiyama M, Suyama K, Nose T, Shimohigashi M, Shimohigashi Y.   +6 more
europepmc   +1 more source

Nuclear Activation Function 2 Estrogen Receptor α Attenuates Arterial and Renal Alterations Due to Aging and Hypertension in Female Mice. [PDF]

J Am Heart Assoc, 2020
Guivarc'h E, Favre J, Guihot AL, Vessières E, Grimaud L, Proux C, Rivron J, Barbelivien A, Fassot C, Briet M, Lenfant F, Fontaine C, Loufrani L, Arnal JF, Henrion D.   +14 more
europepmc   +1 more source

Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells

, 2022
Lucy Barrett, Vanessa S. Fear, Bree Foley, Katherine M. Audsley, Samantha Barnes, Hannah V. Newnes, Alison M. McDonnell, Fiona Wood, Mark W. Fear, Jason Waithman   +9 more
openalex   +1 more source