Results 51 to 60 of about 1,083,914 (265)

Superior stress relaxation resistance of 2.2 GPa martensitic steels and the effect of vanadium

Journal of Materials Research and Technology
For ultra-high-strength steels subjected to sustained loading, stress relaxation resistance is a core indicator determining their long-term service reliability.
Siming Huang, Jianping Ouyang, Liejun Li, Songjun Chen, Xianqiang Xing, Zhuoran Li, Haixiao Ye, Zhengwu Peng, Zhichao Luo   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigation of mechanical activation effect on high-volume natural pozzolanic cements

Open Chemistry, 2022
Mechanical activation is one of the most preferred methods to increase the reactivity of mineral, mining, and industrial wastes or materials with low pozzolanic content in cement production.
Korkmaz Abdul Vahap, Kayıran Huseyin Fırat   +1 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

On the Analysis of the Activation Volume

Zeitschrift für Naturforschung A, 1976
Abstract The stress and temperature dependence of the activation volume is often explained by a similar dependence of the measured stress sensitivity. This explanation cannot be reconciled with the nonconservative motion of jogs, with dislocation climb, nor with the intersection mechanism.
openaire   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Adsorption of Carbon Dioxide onto Activated Carbon Prepared from Coconut Shells

Journal of Chemistry, 2015
This study presents the fabrication of high-quality activated carbon (AC) from discarded coconut shells. The effects of experimental parameters such as activation temperature and activation time on the basic characteristics of AC, including charcoal ...
Pei-Hsing Huang, Hao-Hsiang Cheng, Sheau-Horng Lin   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A Model of Enhanced Strain Rate Sensitivity in Nanocrystalline and Ultrafine-Grained Metals

Reviews on Advanced Materials Science, 2018
A model is suggested that describes enhanced strain rate sensitivity of nanocrystalline and ultrafine-grained metals. Within the model, plastic deformation of such metals incorporates dislocation transmission across grain boundaries (GBs) in the stress ...
Sheinerman A.G., Bobylev S.V.
doaj   +1 more source