Results 71 to 80 of about 1,083,914 (265)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Negative activation volumes of defects in solids
Physical Review B, 1980 A macroscopic model has been recently proposed which permits the calculation of the formation and activation volumes of defects. It is shown that this model can adequately explain the unusual negative activation volume ${v}^{\mathrm{act}}$ observed recently in $B\ensuremath{-}4$ AgI (and earlier in cerium).
VAROTSOS, P, ALEXOPOULOS, K
openaire +2 more sources
Molecular Probing of the Stress Activation Volume in Vapor Phase Lubricated Friction. [PDF]
ACS Appl Mater Interfaces, 2023 Hsu CC +5 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2016 Healthy aging simultaneously affects brain structure, brain function and cognition. These effects are often investigated in isolation ignoring any relationships between them.
Jason Steffener +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Analytical Modeling of Stress Relaxation and Evaluation of the Activation Volume Variation: Effect of Temperature and Plasticizer Content for Poly(3-hydroxybutyrate-3-hydroxyvalerate). [PDF]
ACS Omega, 2022 Aliotta L, Gigante V, Lazzeri A.
europepmc +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Results in Earth SciencesNegative activation volumes for dielectric relaxation are rarely reported in solid state physics and are limited to atomic scale processes. Broadband Dielectric Spectroscopy on heterogeneous systems, such as polycrystalline calcite and magnesite, hosting
Anthony N. Papathanassiou
doaj +1 more source