Results 71 to 80 of about 9,586,286 (339)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Nucleation on active centers in confined volumes [PDF]

The Journal of Chemical Physics, 2012
Kinetic equations describing nucleation on active centers are solved numerically to determine the number of supercritical nuclei, nucleation rate, and the number density of nuclei for formation both of droplets from vapor and also crystalline phase from vapor, solution, and melt.
Kožíšek, Zdeněk, Hikosaka, Masamichi, Okada, Kiyoka, Demo, Pavel   +3 more
openaire   +4 more sources

Activation volume in the density scaling regime: Equation of state and its test by using experimental and simulation data [PDF]

, 2012
In this paper, a formalism for the activation volume of glass forming materials is suggested. An isothermal equation of state for the activation volume is formulated, which is extended to a generalized equation of state that describes the activation ...
A. Grzybowski, K. Koperwas, A. Swiety-Pospiech, K. Grzybowska, M. Paluch   +4 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Investigation of mechanical activation effect on high-volume natural pozzolanic cements

Open Chemistry, 2022
Mechanical activation is one of the most preferred methods to increase the reactivity of mineral, mining, and industrial wastes or materials with low pozzolanic content in cement production.
Korkmaz Abdul Vahap, Kayıran Huseyin Fırat   +1 more
doaj   +1 more source

Negative activation volume for dielectric relaxation in hydrated rocks

, 2010
Negative defect activation volumes are extremely rare in solids. Here, we report for the first time that this holds in a couple of hydrated rocks for dielectric relaxation by exploring the complex impedance spectra at various pressures and temperatures ...
A.N. Papathanassiou, Endres, Fontanella, Fontanella, I. Sakellis, J. Grammatikakis, Morgan, Morgan, Nettelblad, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Papathanassiou, Surkov, Uyeda, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Varotsos, Wang   +42 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation [PDF]

Immunity, 2012
Cell volume regulation is a primitive response to alterations in environmental osmolarity. The NLRP3 inflammasome is a multiprotein complex that senses pathogen- and danger-associated signals. Here, we report that, from fish to mammals, the basic mechanisms of cell swelling and regulatory volume decrease (RVD) are sensed via the NLRP3 inflammasome.
Compan, Vincent, Baroja-Mazo, Alberto, López-Castejón, Gloria, Gomez, Ana I., Martínez, Carlos M., Angosto, Diego, Montero, María T., Herranz, Antonio S., Bazán, Eulalia, Reimers, Diana, Mulero, Victoriano, Pelegrín, Pablo   +11 more
openaire   +2 more sources

Activation volumes in CoPtCr-SiO2 perpendicular recording media [PDF]

, 2005
CoPtCr-SiO2 perpendicular recording media with varying levels of SiO2 were examined by two different methods to determine the activation volume. The first is based on the sweep-rate dependence of the remanence coercivity using Sharrock's equation.
Dutson, J D, Inaba, Y, Muraoka, H, O'Grady, K, Shimatsu, T   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source