Results 151 to 160 of about 5,159,180 (362)

MO046NON-ACTIVATABLE MUTANT OF INHIBITOR OF KAPPA B KINASE α (IKKα) EXERTS SITE-SPECIFIC EFFECTS ON ATHEROSCLEROSIS [PDF]

, 2016
Pathricia V. Tilstam, Wendy Theelen, Setareh Alampour-Sarabi, Lukas Pawig, Yaw Asare, Yvonne Döring, Menno P.J. de Winther, Toby Lawrence, Alma Zernecke, Jürgen Bernhagen, Andreas Schober, Joachim Jankowski, Christian Weber, Heidi Noels   +13 more
openalex   +1 more source

Data from Chemotherapy Rescues Hypoxic Tumor Cells and Induces Their Reoxygenation and Repopulation—An Effect That Is Inhibited by the Hypoxia-Activated Prodrug TH-302

, 2023
Jasdeep K. Saggar, Ian F. Tannock
openalex   +1 more source

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

Proceedings of the National Academy of Sciences of the United States of America, 1981
K. Seamon, W. Padgett, J. Daly
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

P267The transmural activation interval: a new mapping tool to identify protected VT substrates in ARVC [PDF]

, 2017
Jeroen Venlet, AFA Androulakis, Charlotte Brouwer, SRD Piers, Marta Riva, Yoshihisa Naruse, Katja Zeppenfeld   +6 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Electronic and Structural Requirements for Metabolic Activation of Butylated Hydroxytoluene Analogs to Their Quinone Methides, Intermediates Responsible for Lung Toxicity in Mice.

, 1997
Kenji Yamamoto, Sachiko Kato, Kazuo Tajima, Tamio Mizutani   +3 more
openalex   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Correction: From RAAS blockade to regenerative medicine: evolving treatment strategies in Alport syndrome. [PDF]

Pediatr Nephrol
Lo Re C, Kim JJ, Fornoni A.
europepmc   +1 more source

The plasminogen activator/plasmin system.

Journal of Clinical Investigation, 1991
J. Vassalli, A. Sappino, D. Belin
semanticscholar   +1 more source