Results 171 to 180 of about 5,159,180 (362)

Coagulation Markers and Myocardial Blush Grade in STEMI: Identifying Potential Predictors of Microvascular Reperfusion. [PDF]

Clin Appl Thromb Hemost
Doğanözü E, Çiftci O, Bal UA, Aydınalp A, Has Hasırcı S, Özin MB, Haldun Müderrisoğlu I.   +6 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Multi-objective optimal control and application of solid waste synergistically excited fluidized solidified soil. [PDF]

Sci Rep
Liu B, Ye S, Shi H, Chen C, Long Z, He L, Li C.   +6 more
europepmc   +1 more source

IN VITRO AUGMENTATION OF MACROPHAGE-ACTIVATING-FACTOR RELEASE FROM PERIPHERAL BLOOD CELLS OF CANCER PATIENTS BY A DNA FRACTION FROM MYCOBACTERIUM BOVIS BCG

, 1990
Harukazu Mashiba, Keiko Matsunaga, Hirotsugu Tomoda, Motonosuke Furusawa   +3 more
openalex   +2 more sources

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression.

Endocrine reviews, 2003
K. De Bosscher, W. Vanden Berghe, G. Haegeman   +2 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Metal-based (lignin/silica) hybrids as green activators for conductive EPDM composites. [PDF]

Sci Rep
Abdel Zaher KS, Mahmoud DS, El-Sabbagh SH, Ward AA, Nawwar GAM.   +4 more
europepmc   +1 more source

Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer

Annals of the New York Academy of Sciences, 2009
B. Aggarwal, A. Kunnumakkara, K. Harikumar, Shan Gupta, S. Tharakan, C. Koca, S. Dey, Bokyung Sung   +7 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dynamic Control of DNA Origami Self-Assembly by Transcriptional Modules. [PDF]

J Am Chem Soc
Zhang L, Sha R, Bershadsky L, Chaikin PM.   +3 more
europepmc   +1 more source