Results 281 to 290 of about 3,963,692 (395)

Correction: Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila. [PDF]

PLoS Genet
Wu K, Tang Y, Zhang Q, Zhuo Z, Sheng X, Huang J, Ye J, Li X, Liu Z, Chen H.   +9 more
europepmc   +1 more source

The genetics of aflatoxin B1 metabolism. Association of the induction of aflatoxin B1-4-hydroxylase with the transcriptional activation of cytochrome P3-450 gene.

, 1988
Paul L. Koser, M B Faletto, A. E. Maccubbin, Hira L. Gurtoo   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition. [PDF]

J Biol Chem
Haynes LM, Holding ML, Woodard J, Siemieniak D, Ginsburg D.   +4 more
europepmc   +1 more source

Decision-making in interstitial stem cells of hydra [PDF]

, 1991
Bosch, Thomas C. G., David, Charles N.
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

<i>Pseudomonas aeruginosa</i>, my model for research on quorum sensing, biofilms, and opportunistic infections. [PDF]

J Bacteriol
Greenberg EP.
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

How Can Molecules Induce Hemorrhoids? The Role of Genetics and Epigenetics in Hemorrhoidal Disease. [PDF]

Int J Mol Sci
Parol B, Sas O, Mazurek M, Data K, Wozniak S, Domagala Z.   +5 more
europepmc   +1 more source

NF-κB Activation in Lymphoid Malignancies: Genetics, Signaling, and Targeted Therapy

, 2018
Paula Grondona, Philip Bucher, Klaus Schulze‐Osthoff, Stephan Hailfinger, Anja Schmitt   +4 more
openalex   +1 more source