Results 311 to 320 of about 4,610,135 (394)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Exploring the genetic frontier: Unraveling ANRIL, PAI-1, and HNF1α in stroke progression. [PDF]

PLoS One
Hamadi A, Mir R, Al-Amer OM, Alasseiri M, Dobie G, Elfaki I, AlZamzami W, Alatawi S, Oyouni AAA, Alanazi MA, Muthupandian S.   +10 more
europepmc   +1 more source

Dual rare genetic variants: case report of a child with SBIDDS syndrome and citrullinemia type 1. [PDF]

Ital J Pediatr
Boeri S, Siri L, Martinez Popple M, Capra V, Romano F, Fedi C, Nobili L.   +6 more
europepmc   +1 more source

Giant Cell Tumor of Bone: Biology, Pathophysiology, and Histopathology in the Era of H3F3A. [PDF]

Biomedicines
Carneiro BD, Brilhante S, Faria CS, Fonseca S, Pozza DH.   +4 more
europepmc   +1 more source

Forward genetics to identify Listeria monocytogenes components that activate mammalian cytosolic surveillance pathways

, 2011
Chelsea E. Witte
openalex   +1 more source

Heterogeneity in microbial antibiotic responses: genetic basis and within-host evolution. [PDF]

Trends Genet
Liu Q, Lyu LD.
europepmc   +1 more source