Results 211 to 220 of about 3,292,938 (307)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Feasibility of Concurrent 1 H MRS and 31 P MRSI at 7 T: Brain Energy Metabolism Responses to Hyperglycemia. [PDF]

NMR Biomed
Widmaier M, Matson BC, Emir U, Hwang JJ.
europepmc   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Anomalous Enhancement in MXene‐Based Electrochemical Actuators: Pseudo‐Capacitance‐Induced Multi‐Charge Accumulation in Confined Space

Advanced Science, EarlyView.
We elucidate the electrochemical actuation mechanism of 2D material‐based electrodes within a MXene‐centered framework, linking atomic‐scale surface chemistry to macroscopic performance (see schematic). Mechanistically, the reduction of Ti─O─Ti sites in H2SO4 triggers the accumulation of hydrated ions at confined active sites, resulting in anomalous ...
Jiang Xu, Jipeng Feng, Bingqing Hu, Xude Li, Shifei Huang, Shanhai Ge, Guoxiu Wang   +6 more
wiley   +1 more source

Chronic Noise Exposure Induces Anxiety-Like Behavior and Enhances the Excitability of Dorsal Raphe Serotonergic Neurons in Mice. [PDF]

Eur J Neurosci
Yuan Q, Wang SX, Tang ZQ.
europepmc   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

The all-or-none repolarization in cardiac ventricular myocytes: an <i>in silico</i> characterization of a relevant biomarker of ventricular action potential. [PDF]

Front Physiol
Zaniboni M.
europepmc   +1 more source

Hydraulic Pressure‐Programmed Molecular Transport in Tough Hydrogels

Advanced Science, EarlyView.
Hydraulic pressure is introduced as a programmable parameter for regulating molecular transport in tough hydrogel membranes. Reversing the pressure direction accelerates or slows transport, tuning characteristic transport times over a 65‐fold range while achieving molecular separation and controlled delivery.
Yijie Cheng, Shahd Alnasser, Akhiri Zannat, Zhenda He, Jiayi Zeng, Lenan Zhang, Sungmin Hong, Xinyue Liu   +7 more
wiley   +1 more source

Highly attenuated dendritic propagation of isolated synaptic potentials in vivo. [PDF]

Sci Adv
Cornejo VH, Bouazza-Arostegui B, Alejandre-Garcia T, Hao Y, Lee S, Lin MZ, Yuste R.   +6 more
europepmc   +1 more source

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

Advanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet, Hao Ye, Abderrahim Lahlahi Attalhaoui, Donghoon Kim, Vitaly Pustovalov, Elric Zhang, Marc Tudela‐Pi, Bastian Gebauer, Juan Bautista Carda Castelló, Anton Guimerà‐Brunet, Josep Puigmartí‐Luis, Xiang‐Zhong Chen, Minsoo Kim, Salvador Pané   +13 more
wiley   +1 more source