Results 91 to 100 of about 13,165,078 (297)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Frontiers in Neurorobotics, 2018 The CYBERLEGs Beta-Prosthesis is an active transfemoral prosthesis that can provide the full torque required for reproducing average level ground walking at both the knee and ankle in the sagittal plane. The prosthesis attempts to produce a natural level
Louis Flynn +9 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Medicinal Plants, 2019 Background: The effect of Bunium persicum (Boiss.) B. Fedtsch. on the metabolic syndrome and physical fitness of active people have been less studied. Objective: The purpose of this study was to investigate the effect of B.
Maryam Ahmadzadeh +2 more
doaj
Effectiveness of two different recovery process on blood lactate removal pattern of soccer players
Pedagogy of Physical Culture and SportsBackground and Study Aim. Soccer is a high-intensity intermittent sport that requires players to alternate between explosive activity and recovery. This often leads to significant blood lactate accumulation, a by-product of anaerobic metabolism, which ...
Rupali Katoch +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Research on Leakage Monitoring and Identification of Buried Pipeline for Finished Oil Products
Shiyou huagong gaodeng xuexiao xuebaoLeakage of refined oil pipeline can cause environmental pollution and threaten the safety of residents' lives and properties, making leakage monitoring and identification critical.
Gongxing LI
doaj +1 more source
Active Transportation for America [PDF]
, 2008 In this era of traffic congestion, high gas prices, climate change, an obesity epidemic, and fiscal constraints, federal transportation funding has reached a critical crossroads.Decades of car-centered transportation policies have dead-ended in chronic ...
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