Results 101 to 110 of about 12,976,944 (277)

Dialectic Form Finding of Passive and Adaptive Shading Enclosures

open access: yesEnergies, 2014
Form finding describes the process of finding a stable equilibrium shape for a system under a specific set of loads, for a set of boundary conditions and starting from an arbitrary initial geometry.
Sigrid Adriaenssens   +6 more
doaj   +1 more source

Five ways to model active processes in elastic solids: Active forces, active stresses, active strains, active fibers, and active metrics [PDF]

open access: yesMechanics Research Communications, 2018
An important contribution of Gerard Maugin was his study of anelasticity. It is well appreciated that in biological systems, anelasticity manifests itself through growth and remodeling and Maugin and his collaborators have helped build a general theory suitable to model such fundamental processes.
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Biomechanical analysis of different lifting speeds when using an active exoskeleton

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionMusculoskeletal disorders (MSDs), especially lower back pain, are common consequences of repetitive and long-term mechanical stress. Exoskeletons offer a promising approach to reduce this stress by supporting the wearer during physical labour.
Dominik Mayer   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Active, Passive, and Absorptive RIS-Aided 6G Network Under Non-Orthogonal CCI

open access: yesIEEE Open Journal of Vehicular Technology
This paper investigates the impact of randomly deployed non-orthogonal co-channel interference (CCI), originating from the information exchange process among non-orthogonal multiple access (NOMA) users, in an active, passive, and absorptive ...
Volkan Ozduran   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Keeping Students Active, Engaged [PDF]

open access: yes, 2013
Professor Brian Gilbert didn’t start out to be a chemistry professor, but his dynamic style has been influential to students both in the classroom and research ...
Mileham, Mardi
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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