Results 151 to 160 of about 7,575,225 (317)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Portraits of four children from the Cape family [4] [picture] /

open access: yes
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an5770721 ...
Glaister, Thomas, active 1854-1870.
core  

View from balcony, looking south-west, Marble Hill, South Australia [picture] /

open access: yes, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11254186 ...
McGann, Terence, active 1891-1900.
core  

Editorial: Active Aging and Disease Management

open access: yesFrontiers in Medicine, 2018
Helena Canhao   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Government House, Marble Hill, South Australia [picture] /

open access: yes, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11254186 ...
McGann, Terence, active 1891-1900.
core  

A YAP-TEAD-CTCF Transcriptional Regulatory Axis Associated With the Elimination of Injured Hepatocytes From the Liver. [PDF]

open access: yesGenes Cells
Hatakeyama D   +13 more
europepmc   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

On Severn [River], New South Wales, ca. 1848 [picture] /

open access: yes
Title from index.; Rex Nan Kivell Collection NK671/13.; In: Views in New South Wales, Australia, ca. 1848.; Inscription: "On Severn" --In ink below image.; Strathbogie Station was selected in 1839 by Hugh Gordon.; Also known as Thompson.; With: On Guyra ...
Thomson, Edward, active 1840-1870.
core  

Nilpinna Spring, near Cootanoorina [picture] /

open access: yes, 1891
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an6647833 ...
Elliott, Frederick, active 1855-1897.
core  

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