Results 131 to 140 of about 7,575,225 (317)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
View from Government House, Marble Hill, South Australia [picture] /
, 1891 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11254186 ...
McGann, Terence, active 1891-1900.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Bourolong [i.e. Boorolong] Station, New South Wales, ca. 1848 [picture] /
Title from inscription on verso.; Rex Nan Kivell Collection NK 671/3.; Inscription; "Bourolong" -- In ink below image. "Bourolong ; Chas. Marsh Esq." --In index.; In: Views in New South Wales, Australia, ca.
Thomson, Edward, active 1840-1870.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Camp No. 15. - view of range, looking west [picture] /
, 1891 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an6647833 ...
Elliott, Frederick, active 1855-1897.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1894 Title from caption.; Caption note: Initials of Black, the leader of the prospecting team unclear, possibly A.C.; Part of collection: Photographs.; Exhibited: "Travellers Art", National Library of Australia, 12 June 2003-21 September 2003; Exhibited ...
Millar, Roy, active 1884-1900.
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