Results 61 to 70 of about 1,024,616 (247)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Challenges and Achievements of Experimental Implementation of an Active Transfemoral Prosthesis Based on Biological Quasi-Stiffness: The CYBERLEGs Beta-Prosthesis

open access: yesFrontiers in Neurorobotics, 2018
The CYBERLEGs Beta-Prosthesis is an active transfemoral prosthesis that can provide the full torque required for reproducing average level ground walking at both the knee and ankle in the sagittal plane. The prosthesis attempts to produce a natural level
Louis Flynn   +9 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

The Effect of Bunium persicum (Boiss.) B. Fedtsch. Consumption on Metabolic Syndrome Indices, Muscle Strength, and Cardio-respiratory Function in Active Middle-aged Women: A Randomized Clinical Trial

open access: yesJournal of Medicinal Plants, 2019
Background: The effect of Bunium persicum (Boiss.) B. Fedtsch. on the metabolic syndrome and physical fitness of active people have been less studied. Objective: The purpose of this study was to investigate the effect of B.
Maryam Ahmadzadeh   +2 more
doaj  

Effectiveness of two different recovery process on blood lactate removal pattern of soccer players

open access: yesPedagogy of Physical Culture and Sports
Background and Study Aim. Soccer is a high-intensity intermittent sport that requires players to alternate between explosive activity and recovery. This often leads to significant blood lactate accumulation, a by-product of anaerobic metabolism, which ...
Rupali Katoch   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Research on Leakage Monitoring and Identification of Buried Pipeline for Finished Oil Products

open access: yesShiyou huagong gaodeng xuexiao xuebao
Leakage of refined oil pipeline can cause environmental pollution and threaten the safety of residents' lives and properties, making leakage monitoring and identification critical.
Gongxing LI
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The (Non)Active Company of Forces

open access: yesAsian Studies
How do we act when we are defined by the relations that we depend on to flourish? How can we celebrate the nonhuman constitutions that constitute us, but still actively become ourselves and take ethical actions for others? The abundant web of impersonal
Shanni Sunny Tsai
doaj   +1 more source

Atmospheric neutrino data : Active-active × active-sterile oscillations [PDF]

open access: yesNuclear Physics B - Proceedings Supplements, 1999
I summarize here the results of a global fit to the full data set corresponding to 33.0 kt-yr of data of the Super-Kamiokande experiment as well as to all other experiments in order to compare the active-active and active-sterile neutrinos oscillation channels to the atmospheric neutrino anomaly.
openaire   +2 more sources

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