Results 21 to 30 of about 388,268 (259)

No short cuts: building trust in community-based research with ethnocultural groups

International Journal for Equity in Health
Racialized immigrant older adults (RIOAs) in Canada and other Global North countries face significant health inequities, yet remain underrepresented in health research and lack culturally appropriate health programs. While trust-building is essential for
Diya Chowdhury, Joanie Sims-Gould, Heather McKay   +2 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

An implementation mapping approach to equitable program delivery: building readiness in community organizations

Implementation Science Communications
Background Community-based, not-for-profit organizations have potential to advance health equity through delivery of health-promoting interventions to underserved populations.
Thea Franke, Lindsay Nettlefold, Joanie Sims Gould, Karim M. Khan, Heather A. McKay   +4 more
doaj   +1 more source

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

Frontiers in Aging Neuroscience
As global life expectancy increases, Alzheimer’s disease (AD) has become a major public health concern. The gut microbiota plays a pivotal role in regulating the central nervous system, influencing both behavior and cognitive functions in AD through ...
Si-yi Leng, Qi-hang Yang, Qi-hang Yang, Yang Yuan, Bingao Chen, Bingao Chen, Hongbao Chen, Weikang Ban, Jiahao Zhang   +8 more
doaj   +1 more source

A critique of the Active Ageing Index

Journal of Aging Studies, 2017
Active ageing and successful ageing are ubiquitous concepts in contemporary societies. In the European Union, active ageing is monitored and promoted chiefly by the Active Ageing Index, a policy tool in use since 2012. We acknowledge that the AAI may contribute to sensitizing people, including policymakers, to the multidimensionality and complexity of ...
São José, José, Timonen, Virpi, Filipe Amado, Carla Alexandra, Santos, Sergio Pereira   +3 more
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Does optimizing Choose to Move – a health-promoting program for older adults – enhance scalability, program implementation and effectiveness?

International Journal of Behavioral Nutrition and Physical Activity
Background Investment in scale-up and sustainment of effective health-promoting programs is often hampered by competing demands on scarce health dollars.
Lindsay Nettlefold, Heather M. Macdonald, Joanie Sims Gould, Adrian Bauman, Zoe Szewczyk, Heather A. McKay   +5 more
doaj   +1 more source

The mediation and interaction of depressive symptoms in activities of daily living and active aging in rural elderly: A cross-sectional survey

Frontiers in Public Health, 2022
BackgroundCompared with urban areas, old adults in rural areas have limited access to medical and health resources in China. Active of daily living ability (ADL) decline and depressive symptoms are common in rural older adults.
Xuelian Fu, Yinli Su, Chunyan Zeng, Liqiong Liu, Yang Guo, Yuanyuan Wu   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The Impact of Green Exercise on Cardiovascular and Musculoskeletal Health in Middle-Aged and Older Adults: A Scoping Review

European Journal of Investigation in Health, Psychology and Education
Growing urbanization has significantly contributed to the global burden of cardiovascular and musculoskeletal diseases. Green exercise, defined as structured physical activity in natural environments, has emerged as a potential intervention to address ...
Pablo J. Marcos-Pardo, Adrián Mateo-Orcajada, Rodrigo Gomes de Souza Vale, Raquel Vaquero-Cristóbal   +3 more
doaj   +1 more source