Results 21 to 30 of about 400,989 (258)

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

No short cuts: building trust in community-based research with ethnocultural groups

International Journal for Equity in Health
Racialized immigrant older adults (RIOAs) in Canada and other Global North countries face significant health inequities, yet remain underrepresented in health research and lack culturally appropriate health programs. While trust-building is essential for
Diya Chowdhury, Joanie Sims-Gould, Heather McKay   +2 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

An implementation mapping approach to equitable program delivery: building readiness in community organizations

Implementation Science Communications
Background Community-based, not-for-profit organizations have potential to advance health equity through delivery of health-promoting interventions to underserved populations.
Thea Franke, Lindsay Nettlefold, Joanie Sims Gould, Karim M. Khan, Heather A. McKay   +4 more
doaj   +1 more source

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

Frontiers in Aging Neuroscience
As global life expectancy increases, Alzheimer’s disease (AD) has become a major public health concern. The gut microbiota plays a pivotal role in regulating the central nervous system, influencing both behavior and cognitive functions in AD through ...
Si-yi Leng, Qi-hang Yang, Qi-hang Yang, Yang Yuan, Bingao Chen, Bingao Chen, Hongbao Chen, Weikang Ban, Jiahao Zhang   +8 more
doaj   +1 more source

A critique of the Active Ageing Index

Journal of Aging Studies, 2017
Active ageing and successful ageing are ubiquitous concepts in contemporary societies. In the European Union, active ageing is monitored and promoted chiefly by the Active Ageing Index, a policy tool in use since 2012. We acknowledge that the AAI may contribute to sensitizing people, including policymakers, to the multidimensionality and complexity of ...
São José, José, Timonen, Virpi, Filipe Amado, Carla Alexandra, Santos, Sergio Pereira   +3 more
openaire   +3 more sources

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

Does optimizing Choose to Move – a health-promoting program for older adults – enhance scalability, program implementation and effectiveness?

International Journal of Behavioral Nutrition and Physical Activity
Background Investment in scale-up and sustainment of effective health-promoting programs is often hampered by competing demands on scarce health dollars.
Lindsay Nettlefold, Heather M. Macdonald, Joanie Sims Gould, Adrian Bauman, Zoe Szewczyk, Heather A. McKay   +5 more
doaj   +1 more source

The mediation and interaction of depressive symptoms in activities of daily living and active aging in rural elderly: A cross-sectional survey

Frontiers in Public Health, 2022
BackgroundCompared with urban areas, old adults in rural areas have limited access to medical and health resources in China. Active of daily living ability (ADL) decline and depressive symptoms are common in rural older adults.
Xuelian Fu, Yinli Su, Chunyan Zeng, Liqiong Liu, Yang Guo, Yuanyuan Wu   +5 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source