Results 81 to 90 of about 1,085,897 (278)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Identification of main determinants of active aging in the elder population of the castelo branco district, portugal

INFAD, 2015
Reconciling longevity with an independent and independent life is an important objective linked to the aging of the population. This was even assumed by the WHO (2002) when considering active aging as the main objective of the policies directed to the ...
Carlos Manuel Leitão Maia, Florencio Vicente Castro, António Manuel Godinho da Fonseca   +2 more
doaj   +1 more source

Impact of long-term stress on the light output of a WRGB AMOLED display [PDF]

, 2016
This paper describes how long-term use impacts the light output of a commercial 55' WRGB AMOLED display with InGaZnO TFT backplane. This covers effects which are known by the terms 'aging', 'image-sticking,' and 'burn-in.' The focus is on three different
Chesterman, Frédérique, De Visschere, Patrick, Kimpe, Tom, Neyts, Kristiaan, Piepers, Bastian   +4 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Exploring the Feasibility of a Caregiver Burden-Mastery Hybrid Assessment Tool With Decision Matrix in a Memory Clinic: A Multimethod Study

SAGE Open Nursing
Introduction Family members caring for a person living with dementia (PWD) can experience caregiver burden, leading to psychological distress if unmanaged.
Ee Yuee Chan RN, PhD, MSc, MN, BN, Zhi Lei Ong BA, George Frederick Glass RN, MSc, BN (Hons), Siew Ling Ang RN, Jun Pei Lim MMed, MBBS, Noorhazlina Binte Ali MMed, MBBS, Wee Shiong Lim MD, MMed, MHPEd, MBBS   +6 more
doaj   +1 more source

Identification decisive of the active aging in Castelo Branco' senior population.

INFAD, 2017
Reconciling longevity with an independent and independent life is an important objective linked to the aging of the population. This was assumed by WHO (2002) when considering active aging as the main objective of policies directed towards the elderly ...
Carlos Manuel Leitão Maia
doaj   +1 more source

Flight-based chemical characterization of biomass burning aerosols within two prescribed burn smoke plumes [PDF]

, 2011
Biomass burning represents a major global source of aerosols impacting direct radiative forcing and cloud properties. Thus, the goal of a number of current studies involves developing a better understanding of how the chemical composition and mixing ...
Campos, T., Campos, T., Demott, P. J., Demott, P. J., Heymsfield, A. J., Heymsfield, A. J., Kok, G. L., Kok, G. L., Murphy, Shane, Murphy, Shane, Prather, K. A., Prather, K. A., Pratt, K. A., Pratt, K. A., Prenni, A. J., Prenni, A. J., Rogers, D. C., Rogers, D. C., Seinfeld, J. H., Seinfeld, J. H., Subramanian, R., Subramanian, R.   +21 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]

, 2017
Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia, Astiz, Mariana, Imsen, Mercedes, Magnani, Natalia Daniela, Merino, Florencia, Reines, Analia Gabriela, Seilicovich, Adriana, Zarate, Sandra Cristina   +7 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source