Results 61 to 70 of about 3,307,588 (255)

Real Time Detection of Structural Breaks in GARCH Models [PDF]

A sequential Monte Carlo method for estimating GARCH models subject to an unknown number of structural breaks is proposed. Particle filtering techniques allow for fast and efficient updates of posterior quantities and forecasts in real time.
John M. Maheu, Zhongfang He
core   +2 more sources

The Influence of Active Breaks on Neck Pain Relief in Office Settings: A Systematic Review

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background. Non-specific neck pain (NSNP) is a prevalent musculoskeletal condition among office workers, primarily associated with prolonged static postures and sedentary work.
Mehdi Shakerkavar, Aistė Pažėrienė, Vilma Dudonienė   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effectiveness of school-based active breaks on classroom behavior, executive functions and physical fitness in children and adolescent: a systematic review

Frontiers in Public Health
IntroductionThe classroom environment is ideal for promoting physical activity interventions since children spend most of their day there but often engage in sedentary behavior. Given this context, an emerging trend to promote physical activity is active
Tomás Reyes-Amigo, Gabriel Salinas-Gallardo, Edgardo Mendoza, Camilo Ovalle-Fernández, Jessica Ibarra-Mora, Nicolás Gómez-Álvarez, Hernaldo Carrasco-Beltrán, Jacqueline Páez-Herrera, Juan Hurtado-Almonácid, Rodrigo Yañez-Sepúlveda, Rafael Zapata-Lamana, Rafael Zapata-Lamana, Felipe Sepúlveda-Figueroa, Jorge Olivares-Arancibia, Jorge Mota   +14 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Classroom-based physical activity effects: a preliminary overview of previous research

Formare
A growing number of studies show that integrating exercise interventions (such as active breaks) into teaching is associated with physical, mental, emotional, and social benefits and improved cognitive performance in some disciplines, including ...
Rosa Bellacicco, Carlotta Soldano, Melania Talarico, Clarissa Sorrentino   +3 more
doaj   +1 more source

Association of sedentary behaviour patterns with dietary and lifestyle habits among public school teachers: a cross-sectional study

BMJ Open, 2020
Objectives To analyse the association of sedentary behaviour patterns with dietary and lifestyle habits among public school teachers.Design Cross-sectional study.Participants A sample of 245 teachers (186 women and 59 men) with mean age of 45.2 (±10.4 ...
William Rodrigues Tebar, Diego Giulliano Destro Christofaro, Leandro Dragueta Delfino, Fernanda Caroline Gil, Jefferson Marinho De Souza, Marcelo Romanzini, Romulo Araujo Fernandes   +6 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source