Results 231 to 240 of about 14,005,924 (265)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania. [PDF]

PLoS One
Minja LT, Minja LM, Mlalama K, Pamba D, Hella J, Likindikoki S, Nyandindi C, Mbwambo J, Reither K, Belus JM.   +9 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Author Correction: Community-based active-case finding for tuberculosis: navigating a complex minefield. [PDF]

BMC Glob Public Health
MacPherson P, Shanaube K, Phiri MD, Rickman HM, Horton KC, Feasey HRA, Corbett EL, Burke RM, Rangaka MX.   +8 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Community-based active-case finding for tuberculosis: navigating a complex minefield. [PDF]

BMC Glob Public Health
MacPherson P, Shanaube K, Phiri MD, Rickman HM, Horton KC, Feasey HRA, Corbett EL, Burke RM, Rangaka MX.   +8 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Detection of pulmonary tuberculosis through mobile X-ray based active case-finding in Pakistan: a retrospective analysis from programmatic screening of1 214 289 individuals from 2017 to 2021. [PDF]

BMJ Glob Health
Zaidi SMA, Creswell J, Khowaja S, Khan A, Copas A, Esmail H.   +5 more
europepmc   +1 more source

Potential health impacts and costs of active case finding guided by Mycobacterium tuberculosis immunoreactivity survey results in Blantyre, Malawi

Kim S, Can MH, Rickman HM, Phiri MD, Nliwasa M, Mwenyenkulu TE, Mbendera K, Verguet S, Castro MC, Corbett EL, MacPherson P, Cohen T, Menzies NA.   +12 more
europepmc   +1 more source