Results 1 to 10 of about 917,791 (305)

Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background While several recent studies have documented the importance of efflux pumps as mediators of rifampin (RIF) resistance, it remains uncertain which efflux pumps play major roles in rifampin-resistant Mycobacterium tuberculosis strains harboring ...
Fanrong Meng   +16 more
doaj   +1 more source

Bioequivalence and Safety of Two Amisulpride Formulations in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open‑Label, Single‑Dose, Crossover Study

open access: yesDrugs in R&D
Background and Objectives Amisulpride is a second-generation antipsychotic drug that selectively binds to D2 and D3 dopaminergic receptors in the limbic system.
Min Wang   +5 more
doaj   +1 more source

Mycobacterium tuberculosis modulates phosphorylation of host ATP6V1E1 to promote intracellular survival

open access: yesNature Communications
Intracellular pathogens such as Mycobacterium tuberculosis (Mtb) can promote their survival within infected cells by preventing lysosomal acidification. Here, we report that Mtb secretes a protein (Rv1184, or acyltransferase Chp2) that inhibits lysosomal
Jianxia Chen   +22 more
doaj   +1 more source

Single-cell transcriptome sequencing reveals altered peripheral blood immune cells in patients with severe tuberculosis

open access: yesEuropean Journal of Medical Research
Tuberculosis is a serious global health burden, resulting in millions of deaths each year. Several circulating cell subsets in the peripheral blood are known to modulate the host immune response to Mycobacterium tuberculosis (Mtb) infection in different ...
Li Wang   +5 more
doaj   +1 more source

Imaging of thoracic tuberculosis: pulmonary and extrapulmonary. [PDF]

open access: yesBJR Open
Pattamapaspong N   +5 more
europepmc   +1 more source

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