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Mechanisms of Drug-Induced Tolerance in Mycobacterium tuberculosis
Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis populations that are temporarily able to survive antibiotic pressure in the absence of drug resistance-conferring mutations, a phenomenon termed drug tolerance.
Sander N Goossens +2 more
exaly +2 more sources
Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis
Metabolism was once relegated to the supply of energy and biosynthetic precursors, but it has now become clear that it is a specific mediator of nearly all physiological processes. In the context of microbial pathogenesis, metabolism has expanded outside
Sabine Ehrt +2 more
exaly +2 more sources
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues
Conor J Meehan +2 more
exaly +2 more sources
Immune evasion and provocation by Mycobacterium tuberculosis
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra +2 more
semanticscholar +1 more source
Pathogenicity and virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious disease with one of the highest morbidity and mortality rates worldwide.
Kathryn C. Rahlwes +4 more
semanticscholar +1 more source
Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj +1 more source
Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis offers prospects for shortening antibiotic ...
Carlos A. Guerrero-Bustamante +4 more
semanticscholar +1 more source
Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Sebastian M Gygli +2 more
exaly +2 more sources
Mycobacterium abscessus (M. abscessus) is a highly antimicrobial-resistant pathogen that causes refractory pulmonary disease. Recently, the possibility of M. abscessus cross-transmission among cystic fibrosis (CF) patients has been reported.
Keiji Fujiwara +9 more
doaj +1 more source
Causative antigens of humidifier lung in vapor from a humidifier: A case report
A 68-year-old man exhibited fever and cough three weeks prior to hospital admission after three months of ultrasonic humidifier usage. Chest computed tomography showed bilateral ground-glass opacities, lymphocyte levels in the bronchoalveolar lavage ...
Masafumi Shimoda +8 more
doaj +1 more source

