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Mechanisms of Drug-Induced Tolerance in Mycobacterium tuberculosis

open access: yesClinical Microbiology Reviews, 2020
Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis populations that are temporarily able to survive antibiotic pressure in the absence of drug resistance-conferring mutations, a phenomenon termed drug tolerance.
Sander N Goossens   +2 more
exaly   +2 more sources

Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis

open access: yesNature Reviews Microbiology, 2018
Metabolism was once relegated to the supply of energy and biosynthetic precursors, but it has now become clear that it is a specific mediator of nearly all physiological processes. In the context of microbial pathogenesis, metabolism has expanded outside
Sabine Ehrt   +2 more
exaly   +2 more sources

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

open access: yesNature Reviews Microbiology, 2019
Conor J Meehan   +2 more
exaly   +2 more sources

Immune evasion and provocation by Mycobacterium tuberculosis

open access: yesNature Reviews Microbiology, 2022
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra   +2 more
semanticscholar   +1 more source

Pathogenicity and virulence of Mycobacterium tuberculosis

open access: yesVirulence, 2022
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious disease with one of the highest morbidity and mortality rates worldwide.
Kathryn C. Rahlwes   +4 more
semanticscholar   +1 more source

Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?

open access: yesAntibiotics, 2021
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj   +1 more source

Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains

open access: yesmBio, 2021
Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis offers prospects for shortening antibiotic ...
Carlos A. Guerrero-Bustamante   +4 more
semanticscholar   +1 more source

Potential Cross-Transmission of Mycobacterium abscessus among Non-Cystic Fibrosis Patients at a Tertiary Hospital in Japan

open access: yesMicrobiology Spectrum, 2022
Mycobacterium abscessus (M. abscessus) is a highly antimicrobial-resistant pathogen that causes refractory pulmonary disease. Recently, the possibility of M. abscessus cross-transmission among cystic fibrosis (CF) patients has been reported.
Keiji Fujiwara   +9 more
doaj   +1 more source

Causative antigens of humidifier lung in vapor from a humidifier: A case report

open access: yesRespiratory Medicine Case Reports, 2023
A 68-year-old man exhibited fever and cough three weeks prior to hospital admission after three months of ultrasonic humidifier usage. Chest computed tomography showed bilateral ground-glass opacities, lymphocyte levels in the bronchoalveolar lavage ...
Masafumi Shimoda   +8 more
doaj   +1 more source

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