Results 21 to 30 of about 333,738 (190)

In vitro activities of contezolid (MRX-I) against drug-sensitive and drug-resistant Mycobacterium tuberculosis

Microbiology Spectrum, 2023
A novel oxazolidinone for the treatment of Mycobacterium tuberculosis has been developed, but the activity of contezolid (MRX-I) still needs to be clarified.
Huiru An, Wenna Sun, Xiao Liu, Tianhao Wang, Juan Qiao, Jianqin Liang   +5 more
doaj   +1 more source

Ultrasensitive enzyme-linked immunosorbent assay for the detection of MPT64 secretory antigen to evaluate Mycobacterium tuberculosis viability in sputum

International Journal of Infectious Diseases, 2020
Objectives: This study examined Mycobacterium tuberculosis (MTB)-secreted MPT64 as a surrogate of bacterial viability for the diagnosis of active pulmonary TB (PTB) and for follow-up treatment.
Kentaro Sakashita, Rikiya Takeuchi, Keita Takeda, Mikio Takamori, Kensuke Ito, Yuriko Igarashi, Eiji Hayashi, Mari Iguchi, Masahiro Ono, Tetsuya Kashiyama, Masatoshi Tachibana, Jun Miyakoshi, Koichi Yano, Yu Sato, Miyake Yamamoto, Kengo Murata, Akihiko Wada, Kinuyo Chikamatsu, Akio Aono, Akiko Takaki, Hideaki Nagai, Akira Yamane, Masahiro Kawashima, Mariko Komatsu, Kazunari Nakaishi, Satoshi Watabe, Satoshi Mitarai   +26 more
doaj   +1 more source

Mycobacterium abscessus ssp. abscessus infection progressing to empyema from vertebral osteomyelitis in an immunocompetent patient without pulmonary disease: a case report

BMC Pulmonary Medicine, 2019
Background Pleural involvement by non-tuberculous mycobacteria (NTM) in patients without distinct pulmonary disease is extremely rare. Vertebral osteomyelitis (VO) with or without pulmonary disease is also a rare clinical presentation of NTM infection ...
Naoki Kadota, Tsutomu Shinohara, Hiroyuki Hino, Yuichiro Goda, Yoshiro Murase, Satoshi Mitarai, Fumitaka Ogushi   +6 more
doaj   +1 more source

The Role of Mycobacterium Tuberculosis Detection on Oral Mucosa in Diagnosis of Pulmonary Tuberculosis

Indonesian Journal of Dental Medicine, 2023
Background. Tuberculosis is one of the world's health problems, with larger mortality rate than HIV/AIDS. In order to control this disease, a new and inexpensive diagnostic method is needed.
Reiska Kumala Bakti, Bagus Soebadi, Diah Savitri Ernawati, Ni Putu Made Mertaniasih   +3 more
doaj   +1 more source

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. [PDF]

, 2018
Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses ...
Anand, Amitesh, Catoiu, Edward, Dillon, Nicholas, Heckmann, David, Kavvas, Erol S, Mih, Nathan, Monk, Jonathan M, Nizet, Victor, Palsson, Bernhard O, Seif, Yara, Yang, Laurence, Yurkovich, James T   +11 more
core   +2 more sources

Human tuberculosis - an ancient disease, as elucidated by ancient microbial biomolecules [PDF]

, 2009
Tuberculosis is a major cause of death but infected people with effective immunity may remain healthy for years, suggesting long-term coexistence of host and pathogen.
Donoghue, HD
core   +1 more source

How mycobacterium tuberculosis infection could lead to the increasing risks of chronic fatigue syndrome and the potential immunological effects: a population-based retrospective cohort study

Journal of Translational Medicine, 2022
Background Chronic fatigue syndrome (CFS) has been shown to be associated with infections. Tuberculosis (TB) is a highly prevalent infectious disease. Patients with chronic fatigue syndrome and post-tuberculosis experience similar symptoms.
Tse-Yen Yang, Cheng-Li Lin, Wei-Cheng Yao, Chon-Fu Lio, Wen-Po Chiang, Kuan Lin, Chien-Feng Kuo, Shin-Yi Tsai   +7 more
doaj   +1 more source

Cholesterol acquisition by Mycobacterium tuberculosis [PDF]

, 2015
In this issue of Virulence, Ramon-Garcia et al. demonstrate the requirement of a mycobacterial efflux pump during growth on cholesterol.
Larrouy-Maumus, GJ
core   +1 more source

Diagnostic Utility of a Mycobacterium Multiplex PCR Detection Panel for Tuberculosis and Nontuberculous Mycobacterial Infections

Microbiology Spectrum, 2023
The prevalence of nontuberculous mycobacterial diseases is increasing worldwide, and tuberculosis remains highly prevalent. Rapid and accurate microbial diagnoses of both tuberculosis and nontuberculous mycobacterial infections are required.
Yoshifumi Uwamino, Akio Aono, Yu Tomita, Kozo Morimoto, Masahiro Kawashima, Hirofumi Kamata, Yuka Sasaki, Hideaki Nagai, Naoki Hasegawa, Satoshi Mitarai   +9 more
doaj   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source