Results 11 to 20 of about 82,647 (261)
Conformational clamping by a membrane ligand activates the EphA2 receptor [PDF]
Abstract The EphA2 receptor is a promising drug target for cancer treatment, since EphA2 activation can inhibit metastasis and tumor progression. It has been recently described that the TYPE7 peptide activates EphA2 using a novel mechanism that involves binding to the single transmembrane domain of the receptor.
Justin M, Westerfield +10 more
openaire +2 more sources
Molecular determinants of complexin clamping and activation function
Previously we reported that Synaptotagmin-1 and Complexin synergistically clamp the SNARE assembly process to generate and maintain a pool of docked vesicles that fuse rapidly and synchronously upon Ca 2+ influx (Ramakrishnan et al., 2020).
Manindra Bera +4 more
openaire +3 more sources
Active-Clamp Resonant Power Factor Correction Converter With Output Ripple Suppression
An active-clamp resonant power factor correction converter with output ripple suppression is proposed and analyzed. It combines a buck power factor correction (PFC) unit and a resonant dc-dc unit by sharing one active switch.
Keyu Cao +4 more
doaj +1 more source
A novel Pulse-Width-Modulation (PWM) quasi-resonant active-clamp phase-shifted full-bridge converter is presented and analyzed in this paper. In the proposed topology, an active-clamp switch and a clamp capacitor that resonates with the leakage ...
Duong Tran, Nam Vu, Woojin Choi
doaj +1 more source
Background Drosophila dosage compensation is an important model system for defining how active chromatin domains are formed. The male-specific lethal dosage compensation complex (MSLc) increases transcript levels of genes along the length of the single ...
William Jordan, Erica Larschan
doaj +1 more source
A New Asymmetrical Current-fed Converter with Voltage Lifting
This paper presents a new zero voltage switching current-fed DC-DC converter with high voltage gain. In this converter all switches (main and auxiliary) turn on under zero voltage switching and turn off under almost zero voltage switching due to snubber
DELSHAD, M.
doaj +1 more source
Whole-cell and Perforated Patch-clamp Recordings from Acutely-isolated Murine Sino-atrial Node Cells
Cardiac pacemaker cells of the sino-atrial node are responsible for the initiation of the heart beat and express an array of ion channels. The patch-clamp technique is the gold standard method for investigating the function of ion channels expressed in ...
Qadeer Aziz +2 more
doaj +1 more source
Performance of Active Clamp and Interleaved Active Clamp Fly back DC-DC Converters for PV Systems
The Flyback converter topology is a well-known and widely used for AC-DC and DC-DC power converters that cover a broad-spectrum including switching power supplies, photovoltaic (PV) system, electric cars, and fuel cell-based generation systems, and among other applications.
Basem M. Badr +5 more
openaire +2 more sources
Pipeline Vibration Control Using Magnetorheological Damping Clamps under Fuzzy–PID Control Algorithm
Aiming at the problem of low-frequency vibration of the hydraulic pipeline, a new type of semi-active damping magnetorheological (MR) damping clamp structure is designed. The structure size and material of the MR damping clamp were determined.
Fei Gong +5 more
doaj +1 more source
SMA Actuator with Active Clamp
AbstractThe paper deals with modeling and simulation of the Shape Memory Alloy (SMA) actuator for mechatronic systems. The thermal actuator made of Nickel–Titanium (NiTi) wire and new active clamp are heated by electric resistance heating and naturally air-cooled. The paper addresses FEM electro thermal simulation of NiTi actuator with special shape of
Drahoš, Peter +2 more
openaire +1 more source

