Results 281 to 290 of about 4,534,827 (376)

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Calcium-dependent activation of TREK-1 and TREK-2 background potassium channels by calcineurin. [PDF]

Sci Rep
Baukál D, Pergel E, Debreczeni D, Horváth Á, Tóth DJ, Takács PT, Czirják G.   +6 more
europepmc   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

A masking clamp for conditional activation of therapeutic antibodies. [PDF]

Front Immunol
Bloch A, Zimmermann JF, Habermann J, Ullrich E, Kolmar H.   +4 more
europepmc   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

High gain and high efficiency soft switching quadratic boost converter for renewable energy applications. [PDF]

Sci Rep
Elghabsi F, Sahid MR, Ayop R, Alanssari A, Al Takrouri M, Swadi M, Sahhouk MA, Malik H, Jadoun VK.   +8 more
europepmc   +1 more source

Magnetic Flux Guides by Material Extrusion

Advanced Science, EarlyView.
Magnetic flux guidance can increase inductive coupling and forces for magnetic sensors, actuators, and transducers. Here, a magnetic material extrusion method is used to fabricate flux concentration structures of arbitrary shapes with a magnetic permeability of 42. In line with simulation analysis, experimental results show that these materials provide
Jorge Cañada, Steven W. Wright, Michail E. Kiziroglou, Eric M. Yeatman, Luis F. Velásquez‐García   +4 more
wiley   +1 more source

Individual Variation in Intrinsic Neuronal Properties of Nucleus Accumbens Core and Shell Medium Spiny Neurons in Male Rats Prone to Sign- or Goal-Track. [PDF]

eNeuro
María-Ríos CE, Murphy GG, Morrow JD.
europepmc   +1 more source

An experimental approach to multi-input multi-output nonlinear active vibration control of a clamped sandwich beam

Celia Hameury, Giovanni Ferrari, Giulio Franchini, Marco Amabili   +3 more
openalex   +1 more source