Results 101 to 110 of about 3,374,794 (302)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

A Collaborative Online International Learning (COIL) Experience in Early Childhood Teacher Education

Education Sciences
This study explores the use of Collaborative Online International Learning (COIL) as a pedagogical method to enhance intercultural competence among Early Childhood Teacher Education (ECTE) students, with an emphasis on Indigenous perspectives in Norway ...
Kristin Severinsen Spieler, Randi Engtrø, Lovise Lohne Pedersen, Anne Karin Vikstøl Olsen   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Usefulness of C-stopper coil for neurointervention [PDF]

, 2014
C-stopper coil (CSC) which are available for 0.018-inch inner diameter microcenter have been used for neurointervention such as transarterial embolization (TAE) of feeding artery.
Nagata, Izumi, Morikawa, Minoru, Hayashi, Kentaro, Horie, Nobutaka   +3 more
core   +1 more source

Transmitter & Receiver Coil Design for Open Area Concealed Weapon Detection System [PDF]

Individuals carrying guns, knives and other weapon type metal objects are a threat to general public safety and thus the detection of such weapons is a priority in airports, schools and military checkpoints etc.
Pati, Prasanta, Mather, Peter
core   +4 more sources

Ride Comfort Control System Considering Physiological and Psychological Characteristics: Effect of Masking on Vertical Vibration on Passengers

Actuators, 2018
Active seat suspension has been proposed to improve ride comfort for ultra-compact mobility. Regarding the ride comfort of passengers due to vertical vibration, the authors have confirmed from biometry measurements that reduction of the vibration ...
Keigo Ikeda, Ayato Endo, Ryosuke Minowa, Takayoshi Narita, Hideaki Kato   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A multi-port optical microfiber coil resonator

A new type of multi-port optical microfiber resonator is presented. The coupler-based coil resonator was fabricated by coiling a four port microfiber coupler around a low index support rod and then embedding the resulting device in a low refractive index
Brambilla, Gilberto, Ismaeel, Rand, Al-Saab, Feras, Jung, Yongmin, Lee, Timothy   +4 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source