Temperature characterisation of an optically-interrogated Rogowski coil [PDF]
An investigation into the performance of an optically-interrogated Rogowski coil over temperatures up to 80 °C is presented. Preliminary thermal tests reveal that the sensor response is temperature-dependent and the measurement errors are increased at ...
Philip Orr +5 more
core +4 more sources
Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity [PDF]
Vesicular traffic during exocytosis is regulated by Rab GTPase, Sec4p in yeast, which is activated by a guanine nucleotide exchange factor (GEF) called Sec2p. The GEF activity is localized in the N-terminal 160 residues of Sec2p, which lacks sequence similarity with any other GEFs with known structures, and thereby the guanine nucleotide exchange ...
Sato, Yusuke +5 more
openaire +2 more sources
Cohesin ATPase activities regulate DNA binding and coiled-coil configuration
The cohesin complex is required for sister chromatid cohesion and genome compaction. Cohesin coiled coils (CCs) can fold at break sites near midpoints to bring head and hinge domains, located at opposite ends of coiled coils, into proximity.
Xingya Xu +3 more
openaire +2 more sources
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel [PDF]
Transient receptor potential (TRP) channels mediate numerous sensory transduction processes and are thought to function as tetramers. TRP channel physiology is well studied; however, comparatively little is understood regarding TRP channel assembly. Here, we identify an autonomously folded assembly domain from the cold- and menthol-gated channel TRPM8.
Tsuruda, Pamela R. +2 more
openaire +2 more sources
Advanced Spectroscopic Studies into the Degradation of Polyester Melamine Coil Coatings before and after Exposure to Natural and Accelerated Weathering Tests [PDF]
PhDPolymeric coating research requires advanced spectroscopic techniques to perform more efficient and detailed analysis in order to improve knowledge on the component distribution and the degradation of functional groups in the coating.
Zhang, Wanrui
core +4 more sources
Coiled Coil Region of Streptokinase γ-Domain Is Essential for Plasminogen Activation [PDF]
The specific functions of the amino acid residues in the streptokinase (SK) gamma-domain were analyzed by studying the interactions of human plasminogen (HPlg) and SK mutants prepared by charge-to-alanine mutagenesis. SK with mutations of groups of amino acids outside the coiled coil region of SK gamma-domain, SK(K278A,K279A,E281A,K282A), and SK(D360A ...
D H, Wu +6 more
openaire +2 more sources
Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity [PDF]
The cohesin complex plays an important role in sister chromatin cohesion. Cohesin's core is composed of two structural maintenance of chromosome (SMC) proteins, called Smc1 and Smc3. SMC proteins are built from a globular hinge domain, a rod-shaped domain composed of long anti-parallel coiled-coil (CC), and a second globular adenosine triphosphatase ...
Orgil, Ola +3 more
openaire +2 more sources
Stim1 Cytosolic Coiled-Coil Interactions in the Resting and Activated State [PDF]
STIM1 and Orai1 are key components of the Ca2+-release activated Ca2+ (CRAC) current that plays an important role in T cell activation as well as mast cell degranulation. Activation of the CRAC channel forming subunit Orai1 occurs via a physical interaction with the ER transmembrane Ca2+ sensor protein STIM1 when ER Ca2+ stores are depleted.
Fahrner, Marc +4 more
openaire +1 more source
The coil–globule transition in self-avoiding active polymers [PDF]
We study the coil globule transition of an active fully flexible polymer. We show how the Θ -point changes with the strength of the active forces.
S. Das, N. Kennedy, A. Cacciuto
openaire +3 more sources
Role of the N-Terminal Activation Domain of the Coiled-Coil Coactivator in Mediating Transcriptional Activation by β-Catenin [PDF]
The coiled-coil coactivator (CoCoA) is involved in transcriptional activation of target genes by nuclear receptors and the xenobiotic aryl hydrocarbon receptor, as well as target genes of the Wnt signaling pathway, which is mediated by the lymphocyte enhancer factor (LEF)/T cell factor transcription factors and the coactivator beta-catenin.
Catherine K, Yang +2 more
openaire +2 more sources

