Results 41 to 50 of about 3,374,794 (302)
Electrical engineering & Electromechanics, 2019 Aim. The synthesis of single-circuit system of active shielding of magnetic field, generated by group of high voltage power lines, with different spatial arrangement of shielding coil. Methodology.
B. I. Kuznetsov +2 more
doaj +1 more source
Coiled-coil inspired functional inclusion bodies
Microbial Cell Factories, 2020 Background Recombinant protein expression in bacteria often leads to the formation of intracellular insoluble protein deposits, a major bottleneck for the production of soluble and active products.
Marcos Gil-Garcia +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Sequence and length optimization of membrane active coiled coils for triggered liposome release
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2019 Defined and tunable peptide-lipid membrane interactions that trigger the release of liposome encapsulated drugs may offer a route to improving the efficiency and specificity of liposome-based drug delivery systems, but this require means to tailor the performance of the membrane active peptides.
Skyttner, Camilla +5 more
openaire +3 more sources
BMC Psychiatry, 2019 Background The current study aims to systematically assess and compare the antidepressant outcomes of repetitive transcranial magnetic stimulation (rTMS) with the figure-of-eight (F8)-coil and deep transcranial magnetic stimulation (DTMS) with the H1 ...
Helena M. Gellersen +1 more
doaj +1 more source
PLoS Genetics, 2020 Accounting for continual evolution of deleterious L1 retrotransposon families, which can contain hundreds to thousands of members remains a major issue in mammalian biology. L1 activity generated upwards of 40% of some mammalian genomes, including humans
Anthony V Furano +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Active Protection of an ${\rm MgB}_{2}$ Test Coil [PDF]
IEEE Transactions on Applied Superconductivity, 2011 This paper presents results of a study, experimental and computational, of a detect-and-activate-the-heater protection technique applied to a magnesium diboride (MgB(2)) test coil operated in semi-persistent mode. The test coil with a winding ID of 25 cm and wound with ~500-m long reacted MgB(2) wire was operated at 4.2 K immersed in a bath of liquid ...
Dong Keun, Park +3 more
openaire +2 more sources
The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype. [PDF]
PLoS ONE, 2012 Laminins are large heterotrimeric cross-shaped extracellular matrix glycoproteins with terminal globular domains and a coiled-coil region through which the three chains are assembled and covalently linked.
Patricia Santos-Valle +8 more
doaj +1 more source