Results 61 to 70 of about 3,374,794 (302)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Creation of Artificial Receptors Activated by Coiled-coil Peptides and Cellular Regulation

YAKUGAKU ZASSHI, 2015
Exploiting the ability of coiled-coil peptides to induce dimer formation, we designed an artificial epidermal growth factor receptor (EGFR) in which dimerization is essential for increasing the tyrosine kinase activity of its intracellular domain. Using leucine-zipper coiled-coil peptides, the surface-exposed E3 ((EIAALEK)3) tag sequence was fused with
openaire   +3 more sources

Brucella abortus MFP: A Trimeric Coiled-Coil Protein with Membrane Fusogenic Activity

Biochemistry, 2008
The bacterial genus Brucella consists of a group of facultative intracellular pathogens which produces abortion and infertility in animals and a chronic debilitating febrile illness in humans. BMFP is a basic protein of Brucella abortus that belongs to a highly conserved group of homologue proteins of unknown structure and function in proteobacteria ...
Carrica, Mariela del Carmen, Craig, Patricio Oliver, Alonso, Silvia del Valle, Goldbaum, Fernando Alberto, Cravero, Silvio Lorenzo Pedro   +4 more
openaire   +3 more sources

A cytoplasmic coiled‐coil domain is required for histidine kinase activity of the yeast osmosensor, SLN1 [PDF]

Molecular Microbiology, 2002
SummaryThe yeast histidine kinase, Sln1p, is a plasma membrane‐associated osmosensor that regulates the activity of the osmotic stress MAP kinase pathway. Changes in the osmotic environment of the cell influence the autokinase activity of the cytoplasmic kinase domain of Sln1p.
Wei, Tao, Cheryl L, Malone, Addison D, Ault, Robert J, Deschenes, Jan S, Fassler   +4 more
openaire   +2 more sources

Development of an Active Micromagnetic Bearing with a 300 μm Outer Diameter Permanent Micromagnet

Actuators
Micromachines, MEMS and actuators suffer from much more significant relative friction and wear issues than their equivalent macroscopic devices. Active magnetic bearings can be a good option to mitigate friction issues; however, their construction at ...
Efren Diez-Jimenez, Miguel Fernandez-Munoz, Rodrigo Garcia-Gonzalez, Hugo Rodriguez-Bodoque, Jesus del-Olmo-Anguix, Angel Villacastin-Sanchez, Gabriele Barbaraci, Emiliano Pereira, Oscar Manzano-Narro, Diego Lopez-Pascual, Ignacio Valiente-Blanco   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

COIL emission of a modified negative branch confocal unstable resonator [PDF]

, 2007
A modified negative branch confocal unstable resonator (MNBUR) was coupled to the chemical oxygeniodine laser (COIL) device of the German Aerospace Center.
Handke, Jürgen, Pargmann, Carsten, Grünewald, Karin M., Hall, Thomas, Duschek, Frank   +4 more
core  

EXPERIMENTAL RESEARCH OF THE POWER FREQUENCY TECHNOGENIC MAGNETIC FIELD ACTIVE SCREENING IN SYSTEM WITH DIFFERENT CONTROL ALGORITHMS AND WITH A SINGLE COIL

Electrical engineering & Electromechanics, 2015
Purpose. Development of methodology and experimental studies of the layout of the active screening of technogenic power frequency magnetic fields with different control algorithms with a single coil magnetic executive body. Methodology.
B. I. Kuznetsov, T. B. Nikitina, I. V. Bovdyj, A. V. Voloshko, E. V. Vinichenko, D. A. Kotliarov   +5 more
doaj  

Remotely detuned receiver coil for high-resolution interventional cardiac magnetic resonance imaging

Frontiers in Cardiovascular Medicine, 2023
IntroductionInterventional cardiac MRI in the context of the treatment of cardiac arrhythmia requires submillimeter image resolution to precisely characterize the cardiac substrate and guide the catheter-based ablation procedure in real-time ...
Sina Marhabaie, Marylène Delcey, Marylène Delcey, Dounia El Hamrani, Fanny Vaillant, Jean-Christophe Ginefri, Valéry Ozenne, Emma Abell, Marie Poirier-Quinot, Bruno Quesson   +9 more
doaj   +1 more source