Results 51 to 60 of about 3,374,794 (302)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation [PDF]

BMC Molecular Biology, 2008
The coiled-coil coactivator (CoCoA) enhances transcriptional activity of nuclear receptors, the xenobiotic aryl hydrocarbon receptor, and the lymphocyte enhancer factors (LEF) in the Wnt/beta-catenin signaling pathway. CoCoA is comprised of a large central coiled coil domain flanked by N-terminal and C-terminal activation domains (AD).
Yang, Catherine K, Kim, Jeong, Ann, David K, Stallcup, Michael R   +3 more
openaire   +2 more sources

[Design and Investigation of a Hybrid Optical Resonator for Medium Energy COIL] [PDF]

, 2007
High brightness laser radiation of chemical oxygen iodine lasers (COIL) requires resonator types especially adapted to low gain medium and rectangular cavity geometry.
Grünewald, Karin, Handke, Jürgen, Hall, Thomas, Duschek, Frank   +3 more
core  

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif [PDF]

, 2014
Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development.
Kajava, Andrey V., Catherine Habel (587966), Ingrid Felger (92160), Andrey V. Kajava (87242), Myriam Arévalo-Herrera (2576233), Herrera, Sócrates, Catherine Habel, Felger, Ingrid, Corradin, Giampietro, Angélica Castellanos (587967), Moret, Remy, Ingrid Felger, Giampietro Corradin (27387), Sócrates Herrera, Angélica Castellanos, Myriam Arévalo-Herrera, Catherine Servis (273314), Mary Lopez-Perez (123279), Mary Lopez-Perez, Habel, Catherine, Céspedes, Nora, Servis, Catherine, Andrey V Kajava, Sócrates Herrera (2576236), Castellanos, Angélica, Arévalo-Herrera, Myriam, Giampietro Corradin, Remy Moret (587968), Nora Céspedes (587965), Remy Moret, Lopez-Perez, Mary, Catherine Servis, Nora Céspedes   +32 more
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Role of TFG sequences outside the coiled-coil domain in TRK-T3 oncogenic activation [PDF]

Oncogene, 2003
The TRK-T3 oncoprotein, isolated from a human papillary thyroid tumor, arises from the fusion between the N-terminal domain of the TFG gene and the tyrosine kinase domain of the NTRK1 receptor. The 68 kDa TRK-T3 oncoprotein displays a constitutive tyrosine kinase activity resulting in its capability to transform NIH3T3 cells.
Emanuela, Roccato, Sonia, Pagliardini, Loredana, Cleris, Silvana, Canevari, Franca, Formelli, Marco A, Pierotti, Angela, Greco   +6 more
openaire   +2 more sources

Performance of a Modified Negative Branch Unstable Resonator [PDF]

, 2007
Far field deployment of high power chemical oxygen iodine laser (COIL) affords optimally adapted resonator architectures. Such resonators shall enable high brightness operation.
Grünewald, Karin, Handke, Jürgen, Pargmann, Carsten, Hall, Thomas, Duschek, Frank   +4 more
core  

Reactor-scale stellarators with force and torque minimized dipole coils

Nuclear Fusion
In this work, we utilize new coil objectives for stellarator optimization with autodifferentiation, including pointwise and net coil–coil forces and torques. We use these methods to perform the first large-scale optimization of planar dipole coil arrays,
Alan A. Kaptanoglu, Alexander Wiedman, Jacob Halpern, Siena Hurwitz, Elizabeth J. Paul, Matt Landreman   +5 more
doaj   +1 more source

Evaluation and comparison of microbial colonization on nickel titanium (NiTi) closed coil springs and active tie-backs during orthodontic space closure: An in-vivo study

Journal of Orthodontic Science
OBJECTIVE: Literature suggests that the mode of ligation and use of elastomeric chains for achieving orthodontic space closure may result in a significant increase in microbial colonisation.
Genoey George, K. Jithesh Kumar, K. Anjali, Steve M. Jacob, G. Manas, Abhishek Singh Nayyar   +5 more
doaj   +1 more source

Numerical investigation of toroidal plasma response for ELM control via magnetic perturbations in the DTT Tokamak

Nuclear Fusion, 2023
Linear plasma response modeling is exploited in this work to assess the effect of different coil configurations on edge localized mode (ELM) stability in full power operational scenarios for the Divertor Tokamak Test (DTT) facility, presently under ...
L. Pigatto, T. Bolzonella, M. Bonotto, V. Fusco, Y.Q. Liu, G. Marchiori, F. Villone, G. Vlad   +7 more
doaj   +1 more source