Results 151 to 160 of about 58,873 (300)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Moving Object Segmentation and Tracking Using Active Contour and Color Classification Models
, 2012 [[abstract]]This paper presented a video moving object segmentation and tracking system based on the active contour and the color classification models. First, the active contour model is applied to segment the target object in the initial frame.
莊政宏;Chuang, Cheng-Hung
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Ships Tracking Based on Active Contour Model [PDF]
, 2006 将主动轮廓线模型用于海面运动船只的跟踪,提出了一种自动选择主动轮廓线初始控制点的方法,增强了主动轮廓线模型的实用性,并将基于主动轮廓线模型的跟踪方法用于多个海面运动目标的跟踪。实验结果表明,提出的初始主动轮廓线自动选取方法可以准确地选择目标的轮廓线的特征点;基于主动轮廓线模型的跟踪方法可以比较准确地跟踪运动船只的主要轮廓特征。This paper proposes a method based on active contour model to track the moving object on ...
张明杰, 刘明业, 李翠华
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Convolutional neural network initialized active contour model with adaptive ellipse fitting for nuclear segmentation on breast histopathological images. [PDF]
J Med Imaging (Bellingham), 2019 Xu J +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Automatic Lung Segmentation With Juxta-Pleural Nodule Identification Using Active Contour Model and Bayesian Approach. [PDF]
IEEE J Transl Eng Health Med, 2018 Chung H, Ko H, Jeon SJ, Yoon KH, Lee J.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Supervised Texture-Based Active Contour Model With Linear Programming
, 2008 International audienceIn this paper we propose a new supervised active contour model evolving with Haralick texture features. This model is divided in two stages.
Mocquillon, Cédric +4 more
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