Results 161 to 170 of about 58,873 (300)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Cone Photoreceptor Cell Segmentation and Diameter Measurement on Adaptive Optics Images Using Circularly Constrained Active Contour Model. [PDF]

Invest Ophthalmol Vis Sci, 2018
Liu J, Jung H, Dubra A, Tam J.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A colour active contour model for contour extraction in natural scenes

, 1997
The performance of active contours, originally introduced as snakes, depends on the proper selection of model parameters and initial contours. In natural scenes, active contours often fail to converge to the desired solution because of unconstrained ...
Ngoi, Kian Peng
core  

MassSeg-Framework: A Breast Mass Detection and Segmentation Framework Based on Deep Learning and an Active Contour Model. [PDF]

Life (Basel)
Zambrano C, Pérez-Pérez N, Coimbra M, Baldeon-Calisto M, Flores-Moyano R, Mora JR, Camacho O, Benítez D.   +7 more
europepmc   +1 more source

An Active Contour Model Based on Adaptive Threshold for Extraction of Cerebral Vascular Structures. [PDF]

Comput Math Methods Med, 2016
Wang J, Zhao S, Liu Z, Tian Y, Duan F, Pan Y.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Automatic 3D coronary artery segmentation based on local region active contour model. [PDF]

J Thorac Dis
Chen X, Jiang J, Zhang X.
europepmc   +1 more source

A Novel Active Contour Model for MRI Brain Segmentation used in Radiotherapy Treatment Planning. [PDF]

Electron Physician, 2016
Mostaar A, Houshyari M, Badieyan S.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source