Results 71 to 80 of about 58,196 (258)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Improving segmentation accuracy of CT kidney cancer images using adaptive active contour model. [PDF]
Medicine (Baltimore), 2020 Hsu WY, Lu CC, Hsu YY.
europepmc +1 more source
Shape Extraction Via Heat Flow Analogy
, 2007 In this paper, we introduce a novel evolution-based segmentation algorithm by using the heat flow analogy, to gain practical advantage. The proposed algorithm consists of two parts.
Nixon, Mark S, Direkoglu, Cem
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Flame front detection by Line Enhance Active Contour from OH-PLIF images
, 2010 This paper presents a new Line Enhance Active Contour model (LEAC model) to detect the flame front boundaries from high speed Planar Laser Induced Fluorescence (PLIF) images.
Tang YD(唐延东) +2 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Global Inhomogeneous Intensity Clustering- (GINC-) Based Active Contour Model for Image Segmentation and Bias Correction. [PDF]
Comput Math Methods Med, 2020 Feng C +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
FACE CONTOUR TRACKING IN VIDEO USING ACTIVE CONTOUR MODEL
, 2008 Face contour represents important information used for human face analysis in image and video. Here, we propose an improvement to the conventional active contour model, called Snake, to track complex face contour.
Yu Wei +2 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source