Results 31 to 40 of about 160,574 (212)

Fast‐Response Variable‐Stiffness Magnetic Catheters for Minimally Invasive Surgery

open access: yesAdvanced Science
In minimally invasive surgery, such as cardiac ablation, magnetically steered catheters made of variable‐stiffness materials can enable higher dexterity and higher force application to human tissue.
Yegor Piskarev   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating the cooling of solar photovoltaic modules under the conditions of Riyadh

open access: yesJournal of King Saud University: Engineering Sciences, 2023
Cooling enhances the energy conversion efficiency and output of photovoltaic (PV) panels. In this work, the effects of natural convection, forced convection, and evaporative cooling on the performance of polycrystalline PV panels were investigated.
A. Almuwailhi, O. Zeitoun
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Impact of Active and Passive Cooling on Photovoltaic Modules Performance’s

open access: yesЖурнал нано- та електронної фізики
The limitation of the efficiency of photovoltaic modules comes mainly from the thermal or optical (transmission) losses. Overheating of silicon photovoltaic panels due to excessive solar radiation and high ambient temperatures is a major problem.
A. Ghellab, M. Abderrezek
doaj   +1 more source

Numerical Study on Cooling Effect of Downhole Cooling System of Instrument While Drilling

open access: yesShiyou jixie, 2022
Deep and ultra-deep reservoirs have been listed as important replacement areas for oil and gas resources. However, downhole high temperature in deep layers shortens the service life of the instrument while drilling, and even makes it fail.
Liu Ke   +3 more
doaj  

Water-Cooled Thermoelectric Generators for Improved Net Output Power: A Review

open access: yesEnergies, 2021
Thermoelectric generators (TEGs) have the ability to convert waste heat into electrical energy under unfavorable conditions and are becoming increasingly popular in academia, but have not yet achieved a broad commercial success, due to the still ...
Björn Pfeiffelmann   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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