Results 61 to 70 of about 691,660 (297)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Neural Network-Based Active Cooling System With IoT Monitoring and Control for LCPV Silicon Solar Cells

IEEE Access, 2023
One of the methods of increasing output power of solar cells is increasing the concentration ratio using lenses and mirrors. Due to the temperature increase of silicon solar cells with concentrating lenses the system must be provided with an active ...
Gulbakhar Dosymbetova, Saad Mekhilef, Sayat Orynbassar, Ainur Kapparova, Ahmet Saymbetov, Madiyar Nurgaliyev, Batyrbek Zholamanov, Nurzhigit Kuttybay, Sergey Manakov, Yeldos Svanbayev, Nursultan Koshkarbay   +10 more
doaj   +1 more source

The Detectability of AGN Cavities in Cooling-Flow Clusters

, 2009
Chandra X-ray Observatory has revealed X-ray cavities in many nearby cooling flow clusters. The cavities trace feedback from the central active galactic nulceus (AGN) on the intracluster medium (ICM), an important ingredient in stabilizing cooling flows ...
Birzan, L., McNamara, B. R., Nulsen, P. E. J., Rafferty, D. A., Wise, M. W.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Design and Characterization of an Active Cooling System for Temperature-Sensitive Sample Delivery Applications Using Unmanned Aerial Vehicles

Drones
The transport of temperature-sensitive biological samples (blood, medicines, patient samples, vaccines, organs, etc.) to hard-to-reach places remains a challenge.
Ganapathi Pamula, Lakshmi Pamula, Ashwin Ramachandran   +2 more
doaj   +1 more source

High-throughput screening of room temperature active Peltier cooling materials in Heusler compounds

npj Computational Materials, 2022
Active Peltier cooling enables Peltier heat transfer in addition to the traditional Fourier thermal conductance, which is useful in some special applications, such as the microthermostats.
Huifang Luo, Xin Li, Yuxiang Wang, Yeqing Jin, Mingjia Yao, Jiong Yang   +5 more
doaj   +1 more source

Hot Atmospheres, Cold Gas, AGN Feedback and the Evolution of Early Type Galaxies: a Topical Perspective

, 2018
Most galaxies comparable to or larger than the mass of the Milky Way host hot, X-ray emitting atmospheres, and many such galaxies are radio sources. Hot atmospheres and radio jets and lobes are the ingredients of radio-mechanical active galactic nucleus (
Churazov, E., McNamara, B. R., Scannapieco, E., Werner, N.   +3 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Reversing cooling flows with AGN jets: shock waves, rarefaction waves, and trailing outflows

, 2017
The cooling flow problem is one of the central problems in galaxy clusters, and active galactic nucleus (AGN) feedback is considered to play a key role in offsetting cooling.
Duan, Xiaodong, Guo, Fulai, Yuan, Ye-Fei
core   +1 more source

A Deep Look at the Emission-Line Nebula in Abell 2597 [PDF]

, 1997
The close correlation between cooling flows and emission-line nebulae in clusters of galaxies has been recognized for over a decade and a half, but the physical reason for this connection remains unclear.
Allen S., Allen S. W., Begelman M. C., Braine J., Cardiel N., Cowie L. L., Crawford C., Fabian A. C., Fabian A. C., Ferland G. J., G. Mark Voit, Johnstone R. M., Johnstone R. M., Megan Donahue, Pringle J. E., White D. A.   +15 more
core   +2 more sources