Results 101 to 110 of about 12,914,546 (287)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Automated distribution network planning with active network management [PDF]

open access: yes, 2017
Renewable energy generation is becoming a major part of energy supply, often in the form of distributed generation (DG) connected to distribution networks.
Conner, Steven
core   +3 more sources

Investigate on a Simplified Multi-Port Interline DC Power Flow Controller and Its Control Strategy

open access: yesEnergies, 2019
A DC power flow controller (DCPFC) can help to facilitate power flow routing in the multi-terminal high-voltage direct current (HVDC) transmission system.
Wen Wu   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Charging Guidance of Electric Taxis Based on Adaptive Particle Swarm Optimization

open access: yesThe Scientific World Journal, 2015
Electric taxis are playing an important role in the application of electric vehicles. The actual operational data of electric taxis in Shenzhen, China, is analyzed, and, in allusion to the unbalanced time availability of the charging station equipment ...
Liyong Niu, Di Zhang
doaj   +1 more source

Impact of the Converter Control Strategies on the Drive Train of Wind Turbine during Voltage Dips

open access: yesEnergies, 2015
The impact of converter control strategies on the drive train of wind turbines during voltage dips is investigated in this paper using a full electromechanical model.
Fenglin Miao   +2 more
doaj   +1 more source

ADINE - EU Demonstration Project of Active Distribution Network

open access: yes, 2008
The aim of ADINE project is to develop and to demonstrate new methods for the electric distribution network management including distributed generation (DG).
Mäki, N.   +9 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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