Results 91 to 100 of about 2,126,817 (301)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

State-of-Charge Balancing Control of a Modular Multilevel Converter with an Integrated Battery Energy Storage

Energies, 2018
With the fast development of the electric vehicle industry, the reuse of second-life batteries in vehicles are becoming more attractive, however, both the state-of-charge (SOC) inconsistency and the capacity inconsistency of second-life batteries have ...
Hui Liang, Long Guo, Junhong Song, Yong Yang, Weige Zhang, Hongfeng Qi   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Active distribution network with efficient utilisation of distributed generation ancillaryservices

IET Smart Grid, 2018
This study introduces an active distribution network with high penetration of inverter‐based distributed generations (IBDGs) to improve the steady state, dynamic and transient performance of the distribution network. The size and location of the IBDGs, capacitor bank, on‐load tap changers position and voltage regulator set points have been optimised to
Desmond O. Ampofo, Amer Al-Hinai, Mohamed El Moursi   +2 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An associative memory of Hodgkin-Huxley neuron networks with Willshaw-type synaptic couplings

, 2000
An associative memory has been discussed of neural networks consisting of spiking N (=100) Hodgkin-Huxley (HH) neurons with time-delayed couplings, which memorize P patterns in their synaptic weights.
Aihara K., Amari S., Amari S., Amit D. J., Anderson J. A., Aonishi T., Aoyagi T., Brown D., Brunel N., Buhmann J., Calvin W., Cao J., Carr C. E., Eckhorn R., Feng J., Gardner E. J., Gerstner W., Golomb G., Gray C. M., Hasegawa H., Hodgkin A. L., Hopfield J. J., Hoppensteadt F. C., Kanamaru T., Kempter R., Kohonen T., Kohring G. A., Konishi M., Krisement O., Lytton W. W., Maass W., Mueller R., Nadal J., Nemoto I., Perkel D. H., Rieke F., Rolls E. T., Shadlen M., Softky W. R., Softky W. R., Sompolinsky H., Stevens C. F., Suga N., Thorpe S., Treves A., Troyer T. W., Tsodyks M. V., Usher M., Vicente C. J. P., Willshaw D. J., Yoshioka M., Yoshioka M.   +51 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Novel Feature Engineering-Based SOH Estimation Method for Lithium-Ion Battery with Downgraded Laboratory Data

Batteries
Accurate estimation of lithium-ion battery state of health (SOH) can effectively improve the operational safety of electric vehicles and optimize the battery operation strategy.
Jinyu Wang, Caiping Zhang, Xiangfeng Meng, Linjing Zhang, Xu Li, Weige Zhang   +5 more
doaj   +1 more source

A Novel Data-Driven Fast Capacity Estimation of Spent Electric Vehicle Lithium-ion Batteries

Energies, 2014
Fast capacity estimation is a key enabling technique for second-life of lithium-ion batteries due to the hard work involved in determining the capacity of a large number of used electric vehicle (EV) batteries.
Caiping Zhang, Jiuchun Jiang, Weige Zhang, Yukun Wang, Suleiman M. Sharkh, Rui Xiong   +5 more
doaj   +1 more source