Results 71 to 80 of about 497,453 (262)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Distributed Generation Locating and Sizing in Active Distribution Network Considering Network Reconfiguration

open access: yesIEEE Access, 2017
The traditional distributed generation (DG) locating and sizing method is based on a fixed network structure, which is assumed to be unchangeable during the planning period. The flexible distribution network structure is not considered. This paper proposes a novel method for DG locating and sizing in active distribution network (ADN), which mixes DG ...
Haijun Xing, Xin Sun
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

State-of-Charge Balancing Control of a Modular Multilevel Converter with an Integrated Battery Energy Storage

open access: yesEnergies, 2018
With the fast development of the electric vehicle industry, the reuse of second-life batteries in vehicles are becoming more attractive, however, both the state-of-charge (SOC) inconsistency and the capacity inconsistency of second-life batteries have ...
Hui Liang   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Active distribution network with efficient utilisation of distributed generation ancillaryservices

open access: yesIET Smart Grid, 2018
This study introduces an active distribution network with high penetration of inverter‐based distributed generations (IBDGs) to improve the steady state, dynamic and transient performance of the distribution network. The size and location of the IBDGs, capacitor bank, on‐load tap changers position and voltage regulator set points have been optimised to
Desmond O. Ampofo   +2 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Novel Feature Engineering-Based SOH Estimation Method for Lithium-Ion Battery with Downgraded Laboratory Data

open access: yesBatteries
Accurate estimation of lithium-ion battery state of health (SOH) can effectively improve the operational safety of electric vehicles and optimize the battery operation strategy.
Jinyu Wang   +5 more
doaj   +1 more source

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