Results 171 to 180 of about 5,589,366 (302)

Active Faults in Iberia [PDF]

, 2019
Carlos Sanz de Galdeano, José Miguel Azañón, João Cabral, Patricia Ruano, Pedro Alfaro, Carolina Canora, Marta Ferrater, Francisco Juan García Tortosa, Julián García-Mayordomo, Eulàlia Gràcia, Juan Miguel Insua-Arévalo, Alejandro Jiménez Bonilla, Pierre Gilles Lacan, Carlos Marín-Lechado, Raquel Martín-Banda, Fidel Martín González, José J. Martínez-Díaz, Iván Martín-Rojas, Eulàlia Masana, María Ortuño, Antonio Pedrera, Héctor Perea, José Luis Simón   +22 more
openaire   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Ultra-low friction graphene oxide in the Atotsugawa Fault System. [PDF]

Nat Commun
Shimada T, Nagahama H, Muto J, Nakamura N, Sawa S, Ohfuji H.   +5 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Tsunamigenic fault structures revealed in the 2024 Noto earthquake (M7.6) rupture area. [PDF]

Sci Rep
Park JO, Mohammadigheymasi H, Yamaguchi A, Okino K, Fujie G, Jamali Hondori E, Arikawa T, Kurihara T, Imai K.   +8 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Modeling of RC-IGCT-based superconducting hybrid DC circuit breaker with TP KEMA arc model and hybrid SFCL. [PDF]

Sci Rep
Junaid M, Wang X, Yu D, Peng Y.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

A comparative simulation analysis of distributed power flow controller performance on transmission system enhancement. [PDF]

Sci Rep
Vashistha A, Prasad D, Kumar P.
europepmc   +1 more source