Results 191 to 200 of about 610,277 (358)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Seismogeodynamics of interaction area of the Baikal rift northeastern flank and Aldan-Stanovoy block

Литосфера, 2016
The article presents modern structural-tectonic plan and tectonic-dynamic model of the zone of interaction of the most seismicity active northeastern part of the Baikal rift zone (BRZ) and the adjoint system seismogenic structures of the Aldan-Stanovoy ...
L. P. Imaeva, B. M. Koz’Min, V. S. Imaev, N. N. Grib   +3 more
doaj  

SEISMIC DESIGN APPROACH FOR STEEL PIPELINES CROSSING ACTIVE FAULTS

, 2015
Norio Hasegawa, Toshio Imai
openalex   +2 more sources

Robust Fault Protection Technique for Low-Voltage Active Distribution Networks Containing High Penetration of Converter-Interfaced Renewable Energy Resources [PDF]

, 2019
Shijie Cui, Peng Zeng, Chunhe Song, Zhongfeng Wang   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

PV Inverter with Decoupled Active and Reactive Power Control to Mitigate Grid Faults

, 2021
Muhammad Talha, Siti Rohani Sheikh Raihan, Nasrudin Abd Rahim   +2 more
openalex   +1 more source

Active Fault Dislocation-Induced Mechanical Response of Polyurethane-Solidified Track in Tunnels. [PDF]

Materials (Basel)
Chen W, Wu D, Yu M, Wu P, Zhang Y, Luo S, Xu L.   +6 more
europepmc   +1 more source

Recurrent large earthquakes related with an active fault-volcano system, southwest Japan. [PDF]

Sci Rep, 2018
Lin A, Chen P, Sado K.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source