Results 91 to 100 of about 1,574,048 (297)

Evidence of widespread hot plasma in a non-flaring coronal active region from Hinode/XRT

, 2009
Nanoflares, short and intense heat pulses within spatially unresolved magnetic strands, are now considered a leading candidate to solve the coronal heating problem.
Cargill, Cargill, Fabio Reale, Fletcher, James A. Klimchuk, Klimchuk, McTiernan, Orlando, Paola Testa, Parenti, Patsourakos, Reale, Schmelz, Susanna Parenti, , Warren   +14 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Dual-Function Instantaneous Power Theory for Operation of Three-Level Neutral-Point-Clamped Inverter-Based Shunt Active Power Filter

Energies, 2018
This paper proposes a simple yet effective reference current generation algorithm based on instantaneous power pq theory to enhance mitigation performance of a three-phase three-level neutral-point-clamped (NPC) inverter-based shunt active power filter ...
Yap Hoon, Mohd Amran Mohd Radzi, Mohd Khair Hassan, Nashiren Farzilah Mailah   +3 more
doaj   +1 more source

Practical Active Capacitor Filter [PDF]

, 2005
A method and apparatus is described that filters an electrical signal. The filtering uses a capacitor multiplier circuit where the capacitor multiplier circuit uses at least one amplifier circuit and at least one capacitor.
Shuler, Robert L., Jr.
core   +1 more source

Active plasmon injection scheme for subdiffraction imaging with imperfect negative index flat lens

, 2017
We present an active physical implementation of the recently introduced plasmon injection loss compensation scheme for Pendry's non-ideal negative index flat lens in the presence of realistic material losses and signal-dependent noise.
Adams, Wyatt, Ghoshroy, Anindya, Guney, Durdu O., Zhang, Xu   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Six Concepts in Search of an Author

Instruments, 2019
This paper describes several seemingly interesting detector research projects that, after their initial development, seem not to have been pursued.
Fabio Sauli
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Asymmetrical Three-Level Inverter SiC-Based Topology for High Performance Shunt Active Power Filter

Energies, 2019
Power quality conditioner systems, such as shunt active power filters (SAPFs), are typically required to have low power losses, high-power density, and to produce no electromagnetic interference to other devices connected to the grid.
Rodrigo Guzman Iturra, Peter Thiemann
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source