Results 111 to 120 of about 1,586,013 (297)

Biquadratic Filter Applications Using a Fully-Differential Active-Only Integrator [PDF]

open access: yes, 2013
A new class of active filters, real active-only filters is described and possible implementation issues of these filters are discussed. To remedy these issues, a fully-differential active-only integrator block built around current controlled current ...
Ozoguz, S., Toker, A., Yildiz, H. A.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

An Improved Adaptive Harmonic Current Detection Algorithm in Active Filter

open access: yesKongzhi Yu Xinxi Jishu, 2017
It proposed an improved adaptive harmonic current detection algorithm for active filter based on the shortcoming of the existing variable step-size LMS algorithm for harmonic current detection.
TAN Xitang   +4 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

WAYS OF P-Q THEORY MODERNIZATION FOR WORK IN NON-SINUSOIDAL UNBALANCED VOLTAGE CONDITIONS

open access: yesElectrical engineering & Electromechanics, 2013
Two different techniques of P-Q instantaneous power theory mathematical apparatus modernization for shunt active filters are analyzed. Both techniques are equal in nature while different in implementation.
V.S. Kozlov   +2 more
doaj  

New CMOS Realization of Voltage Differencing Buffered Amplifier and Its Biquad Filter Applications [PDF]

open access: yes, 2012
In this paper, new biquad filter configuration using a recently introduced active element, namely Voltage Differencing Buffered Amplifier (VDBA), is proposed.
Kaçar, F., Noori, A., Yeşil, A.
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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