Results 41 to 50 of about 4,505,341 (288)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Electronic Tunability and Cancellation of Serial Losses in Wire Coils

Sensors, 2022
This work presents a novel methodology to adjust the inductance of real coils (electronically) and to cancel out serial losses (up to tens or even hundreds of Ohms in practice) electronically.
Roman Sotner, Jan Jerabek, Ladislav Polak, Radek Theumer, Lukas Langhammer   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A 42.5 nW, 0.5 V Differential Difference Transconductance Amplifier and Its Application in Low-Power Universal Shadow Filter

IEEE Access
This paper presents new low-power universal shadow filters based on an enhanced CMOS structure utilizing multiple-input differential difference current transconductance amplifiers (MI-DDTAs).
Montree Kumngern, Fabian Khateb, Tomasz Kulej, Daniel Arbet   +3 more
doaj   +1 more source

Multi-Level Open End Windings Multi-Motor Drives

Energies, 2019
A multi-level open-end winding converter topology for multiple-motor drives is presented featuring a main multi-level inverter processing the power delivered to the motors and an active filter based on an auxiliary two-level inverter.
Salvatore Foti, Antonio Testa, Salvatore De Caro, Tommaso Scimone, Giacomo Scelba, Giuseppe Scarcella   +5 more
doaj   +1 more source

RF Active Inductors Small-Signal Design by Means of Conformal Transformations

IEEE Access, 2020
In this work we present a synthesis method for the design of RF and microwave Active Inductors (AI) based on S-parameters and conformal transformations. The proposed approach allows to study and define the desired AI characteristics directly managing the
Alfiero Leoni, Vincenzo Stornelli, Leonardo Pantoli, Giorgio Leuzzi, Zlatica Marinkovic   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

K-Band MMIC Active Inductor-Based Bandpass Filter Suitable for Industrial Applications

IEEE Access
The availability of integrated electronic filters for industrial applications is a missing block at microwave frequencies, in spite of the fact that filters have a crucial role in modern transceivers.
L. Pantoli, P. E. Longhi, F. Bolli, G. Leuzzi   +3 more
doaj   +1 more source

An Explicit Output Current-mode Quadrature Sinusoidal Oscillator and a Universal Filter Employing Only Grounded Passive Components - A Minimal Realisation

Advances in Electrical and Electronic Engineering, 2021
The use of voltage differencing current conveyor as an active device to design a current-mode oscillator along with a universal filter with only grounded passive elements is the main focus of this manuscript.
Tajinder Singh Arora, Manish Gupta, Shiv Narain Gupta   +2 more
doaj   +1 more source