Results 141 to 150 of about 753,133 (348)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Optimal siting and sizing of custom power system and smart parking lot in the active distribution network

open access: yesIET Renewable Power Generation
Non‐linear loads, electrical vehicles (EVs) and power electronics are the sources of harmonic generation in the power system. Harmonics are the reason for the disturbance in the technical constraints and quality of the power system.
Ahad Ebrahimi   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Active Filter for Charging Rectifiers Used in Power Supplies

open access: diamond, 2019
Алексей Вячеславович Удовиченко   +1 more
openalex   +2 more sources

Synthetic immittance dipoles using active current elements [PDF]

open access: yes, 2009
Tato diplomová práce pojednává o syntetických imitačních dvojpólech s proudovými aktivními prvky. V úvodní části jsou představeny proudové aktivní prvky MO-CF a DACA jako stavební bloky elektronických obvodů umožňující zpracování signálů o kmitočtech ...
Mráka, Michal
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Active Filters and Hybrid Technology

open access: yesActive and Passive Electronic Components, 1980
P. L. Moran
doaj   +1 more source

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